Ozcan Kara P, Kara T, Kara Gedik G, Sari O, Sahin O
Department of Nuclear Medicine, Selcuklu Medical Faculty, Selcuk University, Selcuklu, Konya, Turkey.
Rev Esp Med Nucl. 2011 Mar-Apr;30(2):94-6. doi: 10.1016/j.remn.2010.10.008. Epub 2011 Feb 20.
A 62 year-old male with prostate cancer, recently complaining lumbar pain with elevated PSA level (6.83 ng/ml) was referred for evaluating bone metastases. Bone scintigraphy with (99m)Tc-MDP demonstrated intense uptake on third lumbar vertebra. Postoperative biopsy of the lesion on third lumbar vertebra revealed adenocarcinoma metastasis. For evaluating distant metastases and restaging, (18)F-FDG PET-CT was performed postoperatively. On PET-CT imaging there were cervical and left parailiac lymph nodes with FDG uptake, destruction on third lumbar vertebra level and intense soft tissue mass FDG uptake on the same area. Additionally, FDG uptake was detected on right iliac crest. On the CT images obtained by integrated PET-CT scanner, this uptake was matching with lytic bone metastases. The superiority of (18)F-FDG PET-CT for demonstrating osteolytic bone metastases compared to bone scintigraphy was presented in a case of prostate cancer in a patient with bone and lymph node metastases.
一名62岁的前列腺癌男性患者,近期因PSA水平升高(6.83 ng/ml)伴腰痛前来评估骨转移情况。(99m)Tc-MDP骨闪烁显像显示第三腰椎有强烈摄取。第三腰椎病变的术后活检显示为腺癌转移。为评估远处转移及重新分期,术后进行了(18)F-FDG PET-CT检查。PET-CT成像显示颈部及左髂旁淋巴结有FDG摄取,第三腰椎水平有骨质破坏,同一区域有强烈的软组织肿块FDG摄取。此外,右髂嵴也检测到FDG摄取。在PET-CT一体化扫描仪获得的CT图像上,这种摄取与溶骨性骨转移相匹配。在一名伴有骨和淋巴结转移的前列腺癌患者中,展示了(18)F-FDG PET-CT在显示溶骨性骨转移方面相对于骨闪烁显像的优势。