耳针对髋关节置换术中芬太尼需求的影响:一项随机对照试验。

The effect of auricular acupuncture on fentanyl requirement during hip arthroplasty: a randomized controlled trial.

机构信息

Department of Anesthesiology and Intensive Care Medicine, Ernst Moritz Arndt University, Greifswald, Germany.

出版信息

Clin J Pain. 2011 Mar-Apr;27(3):262-7. doi: 10.1097/AJP.0b013e3181fd516c.

Abstract

OBJECTIVES

Although auricular acupuncture (AA) is suggested to be effective in treatment of pain, it has not yet been used for intraoperative analgesia. Therefore, we studied whether the AA reduces intraoperative analgesic requirement during total hip arthroplasty (THA).

METHODS

One hundred and twenty patients scheduled for THA were enrolled in this patient-anesthesiologist-blinded study. The patients were randomly assigned to receive needling of specific AA points or a sham procedure (needling of 3 nonacupoints on the ear helix) ipsilateral to the surgery site. Fixed indwelling AA needles were placed in the evening before THA and withdrawn on the day after surgery. The patients received general anesthesia with desflurane, which end-tidal concentration was kept within 3.5 volume % to 5.5 volume % to maintain the Bispectral Index within 40% to 55%. The anesthesiologists were asked to titrate fentanyl to keep the heart rate and blood pressure within 20% of baseline values. The primary outcome was fentanyl amount given during surgery. The secondary outcome measures were incidence of nausea and vomiting and time to first request of analgesics in the recovery room. The success of patients' and anesthesiologist blinding was also documented.

RESULTS

The data of fentanyl requirement of 116 patients were available for the final analysis. Patients from AA group required 15% less fentanyl during surgery than the controls (4.6±1.1 μg/kg vs. 5.2±1.3 μg/kg; mean±SD; P=0.008). Demographic data and secondary outcome measures were comparable in both groups.

DISCUSSION

Regarding the modest clinical effect, AA should be further investigated for its clinical usefulness for complementary analgesia during the surgery.

摘要

目的

虽然耳针(AA)被认为在治疗疼痛方面有效,但尚未用于术中镇痛。因此,我们研究了 AA 是否可以减少全髋关节置换术(THA)期间的术中镇痛需求。

方法

本患者-麻醉师盲法研究纳入了 120 例计划接受 THA 的患者。患者被随机分配接受同侧手术部位的特定 AA 点针刺或假手术(针刺耳轮上的 3 个非穴位)。固定留置 AA 针在 THA 前一天晚上放置,并在手术后第二天取出。患者接受七氟醚全身麻醉,呼气末浓度保持在 3.5%至 5.5%之间,以维持脑电双频指数在 40%至 55%之间。麻醉师被要求滴定芬太尼,以使心率和血压保持在基线值的 20%以内。主要结局是手术期间给予的芬太尼量。次要结局测量是在恢复室中首次请求镇痛的恶心和呕吐发生率以及时间。还记录了患者和麻醉师的盲法成功率。

结果

116 例患者的芬太尼需求数据可用于最终分析。AA 组患者在手术期间需要的芬太尼比对照组少 15%(4.6±1.1 μg/kg 比 5.2±1.3 μg/kg;平均值±标准差;P=0.008)。两组患者的人口统计学数据和次要结局测量结果相似。

讨论

鉴于临床效果适中,应进一步研究 AA 作为手术期间辅助镇痛的临床实用性。

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