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[酷似腺瘤的垂体黑素细胞瘤]

[Pituitary melanocytoma mimicking an adenoma].

作者信息

Coulibaly Béma, Bouvier Corinne, Paula André Maues de, Fernandez Carla, Dufour Henry, Figarella-Branger Dominique

机构信息

Service d'anatomie pathologique et de neuropathologie, CHU de Timone, Marseille, France.

出版信息

Ann Pathol. 2011 Feb;31(1):50-2. doi: 10.1016/j.annpat.2010.09.007. Epub 2011 Jan 26.

Abstract

A 62-year-old woman was referred for a pituitary tumour diagnosed because of a chronic asthenia and visual disorders. Cerebral MRI showed a pituitary tumour compressing the optic chiasm and enhanced after gadolinium injection. Biological findings showed panhypopituitarism and hyperprolactinemia. The diagnostic of pituitary macro-adenoma was performed and the patient was treated with hormone replacement therapy and dopaminergic agonist. Six months later, she presented visual disorders worsening leading to surgical excision. The diagnosis of pituitary melanocytoma was performed after anatomo-clinical confrontation. Post-operative radiation was done.

摘要

一名62岁女性因慢性乏力和视力障碍被转诊,诊断为垂体瘤。脑部磁共振成像(MRI)显示垂体瘤压迫视交叉,注射钆后增强。生物学检查结果显示全垂体功能减退和高催乳素血症。诊断为垂体大腺瘤,患者接受了激素替代疗法和多巴胺能激动剂治疗。六个月后,她出现视力障碍恶化,遂进行手术切除。经解剖学与临床对照后诊断为垂体黑素细胞瘤。术后进行了放疗。

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