Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore, 22 South Greene Street, Baltimore, MD 21201, USA.
Clin Perinatol. 2011 Mar;38(1):103-12, vi. doi: 10.1016/j.clp.2010.12.001.
Evaluation of venous Doppler parameters has significantly contributed to the understanding of the vascular mechanisms that lead to fetal growth restriction (FGR) and subsequent fetal deterioration in the setting of progressive placental dysfunction. Venous redistribution of umbilical venous blood flow away from the fetal liver precedes fetal growth delay. Venous Doppler examination allows adjustment of monitoring intervals in recognition of accelerating fetal deterioration. The timing of delivery in early-onset FGR remains challenging because gestational age has an overriding effect on the neonatal outcome until the late second trimester and randomized trials of specific delivery triggers are lacking.
评估静脉多普勒参数显著有助于理解导致胎儿生长受限（FGR）和随后进行性胎盘功能障碍胎儿恶化的血管机制。脐静脉血流向胎儿肝脏的静脉重新分布先于胎儿生长迟缓。静脉多普勒检查允许调整监测间隔，以识别加速的胎儿恶化。早发型 FGR 的分娩时机仍然具有挑战性，因为直到妊娠中期后期，胎龄对新生儿结局的影响占主导地位，并且缺乏特定分娩触发因素的随机试验。
