Suppr超能文献

[免疫功能正常患者的急性病毒感染]

[Acute viral infections in immunocompetent patients].

作者信息

Díaz A, Zaragoza R, Granada R, Salavert M

机构信息

Servicio de Medicina Intensiva, Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Med Intensiva. 2011 Apr;35(3):179-85. doi: 10.1016/j.medin.2011.01.001. Epub 2011 Feb 24.

Abstract

Viruses play a significant role in serious infections in adults and sometimes lead to the need for hospitalization and admission to intensive care units, especially in cases of severe respiratory distress or encephalopathy. Influenza and parainfluenza viruses, syncytial respiratory virus, herpes viruses and adenovirures are the most frequent causes of these severe infections. A review of the literature has been performed in order to update the epidemiology, pathogenesis and therapeutic approach of viral infections affecting immunocompetent patients. Furthermore, ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in intensive care units and has a high morbidity and mortality rate. It is mainly a bacterial disease, although the potential role of viruses as pathogens or copathogens in VAP is under discussion. Therefore, a brief review of the potential pathogenic role of viruses in VAP has also been performed.

摘要

病毒在成人严重感染中起重要作用,有时会导致患者需要住院并入住重症监护病房,尤其是在出现严重呼吸窘迫或脑病的情况下。流感病毒、副流感病毒、呼吸道合胞病毒、疱疹病毒和腺病毒是这些严重感染最常见的病因。为了更新影响免疫功能正常患者的病毒感染的流行病学、发病机制和治疗方法,我们进行了文献综述。此外,呼吸机相关性肺炎(VAP)是重症监护病房最常见的医院感染,其发病率和死亡率都很高。它主要是一种细菌性疾病,不过病毒作为VAP病原体或共病原体的潜在作用仍在讨论中。因此,我们也对病毒在VAP中的潜在致病作用进行了简要综述。

相似文献

1
[Acute viral infections in immunocompetent patients].
Med Intensiva. 2011 Apr;35(3):179-85. doi: 10.1016/j.medin.2011.01.001. Epub 2011 Feb 24.
2
Respiratory viral infections in immunocompetent and immunocompromised persons.
Am J Med. 1997 Mar 17;102(3A):2-9; discussion 25-6. doi: 10.1016/s0002-9343(97)00003-x.
3
Herpes simplex virus: a marker of severity in bacterial ventilator-associated pneumonia.
J Crit Care. 2011 Aug;26(4):432.e1-6. doi: 10.1016/j.jcrc.2010.10.008. Epub 2010 Dec 3.
4
Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis.
Clin Infect Dis. 2011 May;52 Suppl 4(Suppl 4):S284-9. doi: 10.1093/cid/cir043.
5
Severe Infections Due to Respiratory Viruses.
Semin Respir Crit Care Med. 2022 Feb;43(1):60-74. doi: 10.1055/s-0041-1740982. Epub 2022 Feb 16.
6
Respiratory virus infections in children with cancer or HIV infection.
J Pediatr Hematol Oncol. 2006 Mar;28(3):154-9. doi: 10.1097/01.mph.0000210061.96075.8e.
7
Respiratory viral infections in transplant recipients.
Antivir Ther. 2007;12(4 Pt B):627-38.
8
Respiratory virus infections after marrow transplant: the Fred Hutchinson Cancer Research Center experience.
Am J Med. 1997 Mar 17;102(3A):27-30; discussion 42-3. doi: 10.1016/s0002-9343(97)00007-7.
9
The role of viruses in nosocomial pneumonia.
Curr Opin Infect Dis. 2011 Apr;24(2):152-6. doi: 10.1097/QCO.0b013e328343b6e4.

引用本文的文献

2
Cytomegalovirus and Epstein-Barr virus reactivation in the intensive care unit.
Med Klin Intensivmed Notfmed. 2017 Apr;112(3):239-245. doi: 10.1007/s00063-016-0198-0. Epub 2016 Jul 19.

本文引用的文献

1
Herpes simplex virus: a marker of severity in bacterial ventilator-associated pneumonia.
J Crit Care. 2011 Aug;26(4):432.e1-6. doi: 10.1016/j.jcrc.2010.10.008. Epub 2010 Dec 3.
3
Active cytomegalovirus infection is common in mechanically ventilated medical intensive care unit patients.
Crit Care Med. 2009 Jun;37(6):1850-7. doi: 10.1097/CCM.0b013e31819ffea6.
4
Monitoring of herpes simplex virus in the lower respiratory tract of critically ill patients using real-time PCR: a prospective study.
Clin Microbiol Infect. 2009 Apr;15(4):358-63. doi: 10.1111/j.1469-0691.2009.02704.x. Epub 2009 Mar 2.
6
A silent killer: cytomegalovirus infection in the nonimmunocompromised critically ill patient.
Crit Care Med. 2008 Dec;36(12):3261-4. doi: 10.1097/CCM.0b013e31818f24c3.
7
Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation.
Chest. 2008 Dec;134(6):1141-1148. doi: 10.1378/chest.08-0888. Epub 2008 Aug 8.
8
Herpes simplex virus load in bronchoalveolar lavage fluid is related to poor outcome in critically ill patients.
Intensive Care Med. 2008 Dec;34(12):2202-9. doi: 10.1007/s00134-008-1231-4. Epub 2008 Aug 5.
9
Influenza.
Crit Care Med. 2008 Sep;36(9):2660-6. doi: 10.1097/CCM.0b013e318180b039.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验