Parent-of-origin allelic contributions to deiodinase-3 expression elicit localized hyperthyroid milieu in the hippocampus.
作者信息
Sittig L J, Herzing L B K, Shukla P K, Redei E E
出版信息
Mol Psychiatry. 2011 Aug;16(8):786-7. doi: 10.1038/mp.2011.19. Epub 2011 Mar 1.
Abstract
摘要
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Parent-of-origin allelic contributions to deiodinase-3 expression elicit localized hyperthyroid milieu in the hippocampus.源自亲代的等位基因对脱碘酶-3表达的贡献在海马体中引发局部甲状腺功能亢进环境。
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A custody battle for the mind: evidence for extensive imprinting in the brain.争夺心智的监护权：大脑中广泛印迹的证据。
Neuron. 2010 Aug 12;67(3):359-62. doi: 10.1016/j.neuron.2010.07.026.
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High-resolution analysis of parent-of-origin allelic expression in the mouse brain.高分辨率分析小鼠大脑中亲本来源等位基因的表达。
Science. 2010 Aug 6;329(5992):643-8. doi: 10.1126/science.1190830. Epub 2010 Jul 8.
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Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.产前甲状腺素治疗会使外周和杏仁核的甲状腺激素水平产生差异。
Psychoneuroendocrinology. 2010 Jul;35(6):791-7. doi: 10.1016/j.psyneuen.2009.10.019. Epub 2009 Dec 11.
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The evolution of the DLK1-DIO3 imprinted domain in mammals.哺乳动物中DLK1-DIO3印记基因座的进化。
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Combined treatment with sertraline and liothyronine in major depression: a randomized, double-blind, placebo-controlled trial.舍曲林与三碘甲状腺原氨酸联合治疗重度抑郁症：一项随机、双盲、安慰剂对照试验。
Arch Gen Psychiatry. 2007 Jun;64(6):679-88. doi: 10.1001/archpsyc.64.6.679.
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Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression.超生理剂量的左甲状腺素会改变双相抑郁患者的局部脑代谢并改善情绪。
Mol Psychiatry. 2005 May;10(5):456-69. doi: 10.1038/sj.mp.4001647.
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The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts.编码3型碘甲状腺原氨酸脱碘酶（Dio3）的基因座在胎儿中是印记的，并表达反义转录本。
Endocrinology. 2002 Nov;143(11):4483-6. doi: 10.1210/en.2002-220800.
8
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Curr Biol. 2002 Jul 23;12(14):1221-6. doi: 10.1016/s0960-9822(02)00951-x.
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Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases.碘甲状腺原氨酸脱碘酶的生物化学、细胞与分子生物学及生理作用
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