Department of Pathology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India.
Saudi J Gastroenterol. 2011 Mar-Apr;17(2):110-3. doi: 10.4103/1319-3767.77239.
BACKGROUND/AIM: Intestinal tuberculosis needs to be considered in the differential diagnosis when patients with intestinal pathology are encountered. Tuberculosis can mimic other disease entities like, ischemic enteritis, inflammatory bowel diseases, malignancies, intussusception etc., clinically as well as morphologically in resected intestinal specimens. We aimed to study the various clinical presentations leading to intestinal resection, with identification of different etiological factors by histopathological examination; and to illustrate, discuss and describe the various histopathological features of the lesions in these resected intestinal specimens with clinicopathological correlation.
We studied 100 cases of resected intestinal specimens received during September 2002 to December 2003. We totally encountered 22 request forms with clinical suspicion of ileoceocal tuberculosis.
Abdominal tenderness and mass in ileoceocal region were noted in all cases. In many instances, the cases were operated for acute/subacute intestinal obstruction. Clinical and intra-operative diagnoses of tubercular enteritis, in many instances, were finally diagnosed histopathologically as ischemic enteritis (nine cases), chronic nonspecific enteritis (four cases), adenocarcinoma of the caecum, Crohn's disease, intussusception (each one case), and correctly as intestinal tuberculosis in only six cases.
Tuberculosis can mimic various disease entities, clinically and sometimes morphologically. Vice versa is also true. An increased awareness of intestinal tuberculosis coupled with varied clinical presentations, nonspecific signs and symptoms, difficulties in diagnostic methods and need of early and specific treatment should improve the outcome for patients with this disease.
背景/目的:当遇到肠道病变的患者时,需要考虑肠道结核的鉴别诊断。在临床上以及在切除的肠道标本的组织学上,结核可能会模仿其他疾病实体,如缺血性肠炎、炎症性肠病、恶性肿瘤、肠套叠等。我们旨在研究导致肠切除的各种临床表现,通过组织病理学检查确定不同的病因;并说明、讨论和描述这些切除的肠道标本中病变的各种组织病理学特征,并与临床病理学相关联。
我们研究了 2002 年 9 月至 2003 年 12 月期间收到的 100 例切除的肠道标本。我们总共遇到了 22 份带有回盲部结核临床怀疑的申请单。
所有病例均有腹痛和回盲部肿块。在许多情况下,这些病例是因急性/亚急性肠梗阻而行手术。在许多情况下,临床和术中诊断为结核性肠炎,最后在组织病理学上诊断为缺血性肠炎(9 例)、慢性非特异性肠炎(4 例)、盲肠癌、克罗恩病、肠套叠(各 1 例),而只有 6 例正确诊断为肠结核。
结核可能会模仿各种疾病实体,在临床上和有时在形态学上。反之亦然。对肠道结核的认识增加,加上不同的临床表现、非特异性体征和症状、诊断方法的困难以及早期和特异性治疗的需要,应改善这种疾病患者的预后。