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肝段 2-3 移植物的获取和植入的实质内技术:解剖基础和手术步骤。

Parenchyma-wise technique for the harvest and implantation of hepatic segment 2-3 grafts: Anatomic basis and surgical steps.

机构信息

Centers for Surgical Anatomy and Technique, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Clin Anat. 2011 Sep;24(6):748-56. doi: 10.1002/ca.21139. Epub 2011 Mar 3.

Abstract

We propose a technique for pediatric liver transplantation that does not waste the donor's parenchyma. Organ shortage has extended criteria for donor acceptance, such that even individuals with livers of suboptimal volume can donate their segment 2-3. By incorporating wise use of parenchyma, our proposed technique for harvesting segment 2-3 for implantation in a pediatric recipient benefits these and other donors, and it might increase donations. This is especially important in countries in which procurement of organs from the deceased is not allowed. Our technique also aims to solve the problem of the large-for-size syndrome for neonates and extremely small infants and to allow for primary closure of the abdomen. This technique enables harvest of the following four grafts: (1) complete segment 2-3; (2) reduced segment 2-3; (3) complete segment 3; and (4) reduced segment 3. The surgeon will select the type that has suitable graft-to-recipient weight ratio and that suits the donor's liver anatomy and volume. These four types benefit the donor by preserving the parenchyma of segment 4 and the left part of the caudate lobe. The three graft types other than the complete segment 2-3 graft will also preserve varying fractions of the parenchyma of segment 2-3. The technique for complete segment 2-3 graft can be put into practice immediately; the techniques for the other three grafts need an imaging modality to preoperatively delineate the donor's fourth-order bile ducts. We expect to correct this deficiency in the near future by developing the requisite imaging technique.

摘要

我们提出了一种不浪费供体实质的小儿肝移植技术。器官短缺已经扩展了供体接受的标准,以至于即使是体积不太理想的肝脏也可以捐献他们的 2-3 段。通过明智地利用实质,我们提出的用于采集 2-3 段并植入小儿受者的技术有利于这些和其他供者,并且可能会增加捐赠。在不允许从死者获取器官的国家,这一点尤其重要。我们的技术还旨在解决新生儿和极小婴儿的“大肝小身”综合征问题,并允许腹部一期关闭。该技术可用于采集以下四种移植物:(1)完整的 2-3 段;(2)减小的 2-3 段;(3)完整的 3 段;和(4)减小的 3 段。外科医生将根据适合供者肝脏解剖和体积的供体-受体重量比选择合适的类型。这四种类型通过保留 4 段和尾状叶左侧的实质来保护供体。除完整的 2-3 段移植物外,其余三种移植物类型也会保留不同比例的 2-3 段实质。完整的 2-3 段移植物技术可以立即实施;其他三种移植物技术需要一种成像方式来术前描绘供体的四级胆管。我们期望在不久的将来通过开发必要的成像技术来纠正这一不足。

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