Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA.
J Vet Intern Med. 2011 Mar-Apr;25(2):169-86. doi: 10.1111/j.1939-1676.2011.00691.x.
Portal hypertension (PH) is the result of increased vascular resistance in the portal circulation, increased portal venous blood flow, or both. In veterinary medicine, where portal pressure is seldom measured directly, the diagnosis of PH often is inferred from identification of associated complications including multiple acquired portosystemic shunts, ascites, and hepatic encephalopathy. Likewise, treatment of PH primarily is aimed at controlling these complications. The goal of this review is to provide an update on the pathophysiology, diagnosis, and treatment of PH. The review draws from information in the veterinary hepatology literature, reviews, and consensus statements in human hepatology and the literature on experimental models of PH.
门静脉高压症（PH）是门静脉循环中血管阻力增加、门静脉血流增加或两者共同作用的结果。在兽医领域，由于很少直接测量门静脉压力，PH 的诊断通常是从识别相关并发症推断出来的，包括多发性获得性门体分流、腹水和肝性脑病。同样，PH 的治疗主要旨在控制这些并发症。本综述的目的是提供门静脉高压症的病理生理学、诊断和治疗的最新信息。本综述借鉴了兽医肝病学文献、人类肝病学的综述和共识声明以及 PH 实验模型文献中的信息。
