Brothers M F, Holgate R C
Department of Radiology, Medical University of South Carolina, Charleston 29425.
AJNR Am J Neuroradiol. 1990 Mar-Apr;11(2):239-47.
Angioplasty of the proximal portions of major cerebral arteries at the base of the brain has shown promise as a therapy for symptomatic vasospasm after subarachnoid hemorrhage. The blind-ended, single-lumen balloon-dilatation catheter most widely used to date lacks steerability, limiting its application to unbranched stems and single branches at bi- or trifurcation points. To extend the capabilities of cerebral angioplasty, we describe two modifications of the basic technique that have allowed increased selectivity and successful angioplasty of multiple branches, both proximal and distal, involved by vasospasm. Of four patients treated, three showed early improvement in their clinical condition, likely attributable to the angioplasty procedure. Our modifications to the basic angioplasty technique enhanced its success. Further refinement of this technique in the treatment of vasospasm will make it safer in treating this serious and widespread disorder.
对脑底部主要脑动脉近端进行血管成形术,已显示出有望成为蛛网膜下腔出血后症状性血管痉挛的一种治疗方法。迄今为止最广泛使用的盲端单腔球囊扩张导管缺乏可操控性,限制了其应用于未分支的主干以及双分支或三分支处的单个分支。为了扩展脑血管成形术的能力,我们描述了对基本技术的两种改进,这使得血管痉挛所累及的近端和远端多个分支的选择性增加且血管成形术得以成功实施。在接受治疗的4例患者中,3例临床状况早期得到改善,这可能归因于血管成形术。我们对基本血管成形术技术的改进提高了其成功率。在血管痉挛治疗中对该技术的进一步完善将使其在治疗这种严重且广泛存在的疾病时更安全。