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辅助性 T 细胞(Th)1、Th2 和 Th17 细胞因子途径与轻度/微小子宫内膜异位症不孕患者的相关性。

T helper (Th)1, Th2, and Th17 interleukin pathways in infertile patients with minimal/mild endometriosis.

机构信息

Programa de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

出版信息

Fertil Steril. 2011 Jun 30;95(8):2477-80. doi: 10.1016/j.fertnstert.2011.02.019. Epub 2011 Mar 10.

Abstract

In the present study, interleukin (IL)-10, IL-12, IL-17, and IL-23 levels were measured in serum and peritoneal fluid of women with minimal or mild endometriosis and compared with levels in controls without endometriosis. Higher IL-23 levels were encountered in the peritoneal fluid of women with endometriosis, suggesting a possible role of this cytokine in these women's infertility.

摘要

在本研究中,我们测量了患有轻度或极轻度子宫内膜异位症的女性血清和腹腔液中的白细胞介素 (IL)-10、IL-12、IL-17 和 IL-23 水平,并与无子宫内膜异位症的对照组进行了比较。患有子宫内膜异位症的女性腹腔液中 IL-23 水平较高,提示这种细胞因子可能在这些女性不孕中发挥作用。

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