Demirci Oya, Ünal Ayşegül, Demirci Elif, Sözen Hamdullah, Akdemir Yeşim, Boybek Esra, Ertekin Aktuğ
Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
J Obstet Gynaecol Res. 2011 Jul;37(7):809-14. doi: 10.1111/j.1447-0756.2010.01440.x. Epub 2011 Mar 13.
To study the relationship between cervical lengths measured by ultrasound and risk of preterm delivery.
MATERIAL & METHODS: We examined 209 women with singleton pregnancies. The inclusion criteria were women who presented with regular and painful contractions (≥2 contractions at intervals of 10 min for at least 1 h). Transvaginal scan was performed to measure the cervical length. The clinical management of the women, including hospitalization and administration of tocolytics, was determined by the attending obstetricians, who were blinded about cervical length. The primary outcome was delivery within 7 days of presentation.
Delivery within 7 days of presentation occurred in 19/209 (9%) of pregnancies who were presenting with regular and painful uterine contraction at 31 weeks of gestation, and this was inversely related to cervical length. Logistic regression analysis demonstrated that cervical length and history of abortion remain as significant contributors to predicting delivery within 7 days. Of the patients who presented with threatened preterm labor, 117 (56%) received tocolytics, and 92 (44%) did not. In the group with a cervical length of <15 mm, delivery within 7 days occurred in 15/21 (71.4%) who were treated with tocolytics and 2/5 (40%) that were managed expectantly.
Women with threatened preterm labor and a cervical length of <15 mm at presentation are at high risk of delivering preterm within 7 days. Sonographic measurement of cervical length helps to avoid over-diagnosis of preterm labor.
研究超声测量宫颈长度与早产风险之间的关系。
我们检查了209名单胎妊娠女性。纳入标准为出现规律且疼痛宫缩的女性(间隔10分钟至少有2次宫缩,持续至少1小时)。经阴道扫描测量宫颈长度。这些女性的临床管理,包括住院和使用宫缩抑制剂,由主治产科医生决定,他们并不知晓宫颈长度。主要结局是就诊后7天内分娩。
在妊娠31周出现规律且疼痛宫缩的孕妇中,19/209(9%)在就诊后7天内分娩,这与宫颈长度呈负相关。逻辑回归分析表明,宫颈长度和流产史仍然是预测7天内分娩的重要因素。在出现先兆早产的患者中,117名(56%)接受了宫缩抑制剂治疗,92名(44%)未接受治疗。在宫颈长度<15mm的组中,接受宫缩抑制剂治疗的21名患者中有15名(71.4%)在7天内分娩,5名接受期待治疗的患者中有2名(40%)在7天内分娩。
出现先兆早产且就诊时宫颈长度<15mm的女性在7天内早产风险高。超声测量宫颈长度有助于避免早产的过度诊断。