Say Emil Anthony T, Shields Carol L, Bianciotto Carlos, Shields Jerry A
Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
J AAPOS. 2011 Feb;15(1):107-8. doi: 10.1016/j.jaapos.2010.11.010.
Periocular corticosteroid injection is a potent and versatile treatment for uveitic conditions as well as for some ocular tumors. Despite its efficacy, ophthalmologists are wary of documented side effects, some of which can be blinding. Adverse reactions are mostly dependent on route of administration, with glaucoma and cataract formation more often seen in peribulbar and intraocular injections, whereas skin depigmentation and fat atrophy are more frequently related to intradermal or intralesional routes, particularly after injection of capillary hemangioma of infancy. We present a child with perilymphatic linear subcutaneous fat atrophy and depigmentation after sub-Tenon's fascia injection of triamcinolone acetonide.
眼周皮质类固醇注射是治疗葡萄膜炎以及某些眼部肿瘤的一种强效且用途广泛的方法。尽管其疗效显著,但眼科医生对已记录的副作用仍心存顾虑,其中一些副作用可能导致失明。不良反应大多取决于给药途径,青光眼和白内障形成在球周和眼内注射中更为常见,而皮肤色素脱失和脂肪萎缩则更常与皮内或病灶内注射途径相关,尤其是在注射婴儿期毛细血管瘤后。我们报告一例患儿,在Tenon囊下注射曲安奈德后出现淋巴管周围线性皮下脂肪萎缩和色素脱失。