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骨质疏松症患者的面部骨骼:疾病体征与治疗并发症的一个领域。

The facial skeleton in patients with osteoporosis: a field for disease signs and treatment complications.

作者信息

Kyrgidis Athanassios, Tzellos Thrasivoulos-George, Toulis Konstantinos, Antoniades Konstantinos

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.

出版信息

J Osteoporos. 2011 Feb 16;2011:147689. doi: 10.4061/2011/147689.

Abstract

Osteoporosis affects all bones, including those of the facial skeleton. To date the facial bones have not drawn much attention due to the minimal probability of morbid fractures. Hearing and dentition loss due to osteoporosis has been reported. New research findings suggest that radiologic examination of the facial skeleton can be a cost-effective adjunct to complement the early diagnosis and the follow up of osteoporosis patients. Bone-mass preservation treatments have been associated with osteomyelitis of the jawbones, a condition commonly described as osteonecrosis of the jaws (ONJ). The facial skeleton, where alimentary tract mucosa attaches directly to periosteum and teeth which lie in their sockets of alveolar bone, is an area unique for the early detection of osteoporosis but also for the prevention of treatment-associated complications. We review facial bone involvement in patients with osteoporosis and we present data that make the multidisciplinary approach of these patients more appealing for both practitioners and dentists. With regard to ONJ, a tabular summary with currently available evidence is provided to facilitate multidisciplinary practice coordination for the treatment of patients receiving bisphosphonates.

摘要

骨质疏松症会影响所有骨骼,包括面部骨骼。由于发生病理性骨折的可能性极小,迄今为止面部骨骼尚未引起太多关注。已有报道称骨质疏松症会导致听力丧失和牙齿脱落。新的研究结果表明,对面部骨骼进行放射学检查可以作为一种经济有效的辅助手段,以补充骨质疏松症患者的早期诊断和随访。骨量保存治疗与颌骨骨髓炎有关,这种情况通常被称为颌骨坏死(ONJ)。面部骨骼是消化道黏膜直接附着于骨膜且牙齿位于牙槽骨牙槽窝中的部位,它不仅是早期检测骨质疏松症的独特区域,也是预防治疗相关并发症的独特区域。我们回顾了骨质疏松症患者面部骨骼受累的情况,并提供了相关数据,这些数据使得对这些患者采取多学科方法对医生和牙医都更具吸引力。关于ONJ,提供了一个包含当前可用证据的表格总结,以促进接受双膦酸盐治疗患者的多学科实践协调。

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