Research Unit of Radiology and Medical Imaging, Evgenidion University Hospital Athens, Greece.
Pain Physician. 2011 Mar-Apr;14(2):211-5.
The pudendal nerve may be strained either between the sacrospinous and sacrotuberous ligaments at the ischial spine level or within Alcock's canal. Alcock's neuralgia is a rare, painful condition caused by compression of the pudendal nerve within Alcock's canal (pudendal canal) which is an aponeurotic tunnel that cannot be stretched. Patients usually present with intense, unilateral pain involving anatomic areas along the pudendal nerve's root, genital, anal, and pelvic regions causing mobility impairment. A computed tomography (CT)--guided percutaneous infiltration of the pudendal nerve with a mixture of a local anesthetic and a long-acting corticosteroid is a safe and efficient method that reduces the pain caused by the neuralgia. Corticosteroids and local anesthetics interfere with the neurons, the encoding, and the processing of noxious stimuli; interrupt the pain-spasm cycle; and reduce inflammation. The injected glucocorticosteroid may take 3-5 days to reach its anti-inflammatory effect; therefore, the initial pain relief from the local anesthetic is followed by a baseline pain return and then secondary pain relief at 3-5 days. The procedure is performed under minimal or no anesthesia. In general, at discharge, a responsible person must accompany the patient and ensure a safe return home. Clinical evaluation is performed after 7-10 days. There are 2 types of potential complications that are associated with percutaneous steroid infiltrations: intra-operative (associated with needle placement) and post-operative (infection, bleeding and those associated with the injectate administration). In all cases that steroids were administered within therapeutic doses, no complications were noted. In conclusion, CT-guided percutaneous infiltration with a mixture of long-acting corticosteroid and local anesthetic seems to be a safe and efficient method for the treatment of Alcock's neuralgia.
阴部神经可能在坐骨棘水平的骶棘韧带和骶结节韧带之间或在 Alcock 管内受到拉伤。Alcock 神经痛是一种罕见的疼痛性疾病,由阴部神经在 Alcock 管(阴部管)内受压引起,阴部管是一个不能伸展的腱膜隧道。患者通常表现为强烈的单侧疼痛,涉及阴部神经根部、生殖器、肛门和骨盆区域的解剖区域,导致活动障碍。在 CT 引导下,对阴部神经进行经皮渗透注射,混合使用局部麻醉剂和长效皮质类固醇,是一种安全有效的方法,可减轻神经痛引起的疼痛。皮质类固醇和局部麻醉剂会干扰神经元、编码和有害刺激的处理;中断疼痛-痉挛循环;并减少炎症。注射的糖皮质激素可能需要 3-5 天才能达到抗炎效果;因此,局部麻醉剂最初缓解疼痛后,基线疼痛会恢复,然后在 3-5 天会再次缓解疼痛。该过程在最小或无麻醉下进行。一般来说,出院时,必须有负责人陪同患者并确保安全回家。在 7-10 天后进行临床评估。经皮类固醇渗透注射有两种潜在的并发症:术中(与针放置相关)和术后(感染、出血和与注射剂给药相关)。在所有给予治疗剂量类固醇的情况下,均未出现并发症。总之,CT 引导下经皮渗透注射长效皮质类固醇和局部麻醉剂似乎是治疗 Alcock 神经痛的一种安全有效的方法。