Phase II clinical study of high-dose toremifene in patients with advanced breast cancer.
作者信息
Modig H, Borgström S, Nilsson I, Westman G
机构信息
Department of Oncology, Umeå University Hospital, Sweden.
出版信息
J Steroid Biochem. 1990 Jun 22;36(3):237-8. doi: 10.1016/0022-4731(90)90015-k.
PMID:2142243
Abstract
Thirteen postmenopausal women with advanced local or metastatic breast cancer were treated with the antiestrogen toremifene at a daily dose of 200 mg. All patients had failed previous treatment with different types of endocrine therapy and/or cytotoxic drugs. Objective response was only seen in one patient. Treatment was usually well tolerated but in three cases the drug had to be withdrawn due to side effects.
摘要
Zotero 插件