Department of Chemical Engineering, Queen's University Kingston, ON K7L3N6, Canada.
Macromol Rapid Commun. 2011 Apr 4;32(7):604-9. doi: 10.1002/marc.201000786. Epub 2011 Mar 7.
The use of copper tubing as both the reactor and as a catalyst source is demonstrated for continuous controlled radical polymerization of methyl acrylate at ambient temperature and at low solvent content of 30%. The high surface area provided by the copper walls mediates the reaction via the single electron transfer-living radical polymerization (SET-LRP) mechanism. The polymerizations proceeded quickly, reaching 67% conversion at a residence time of 16 min. Ligand concentration could also be reduced without a sharp drop in polymerization rate, demonstrating the potential for decreased raw material and post-process purification costs. Chain extension experiments conducted using synthesized polymer showed high livingness. The combination of living polymer produced at high polymerization rates at ambient temperature and low volatile organic solvent content demonstrate the potential of a copper reactor for scale up of SET-LRP.
将铜管用做反应器和催化剂源，用于在环境温度和低至 30%的溶剂含量下连续可控自由基聚合甲基丙烯酸甲酯。铜壁提供的高表面积通过单电子转移-活性自由基聚合（SET-LRP）机制来介导反应。聚合反应迅速进行，在停留时间为 16 分钟时达到 67%的转化率。降低配体浓度也不会导致聚合速率急剧下降，这表明有可能降低原材料和后处理纯化成本。使用合成聚合物进行的链延长实验显示出高的活性。在环境温度下以高聚合速率和低挥发性有机溶剂含量生产的活性聚合物的组合，展示了铜反应器在 SET-LRP 放大方面的潜力。
