Plaisant F
Service de néonatalogie et de réanimation néonatale, hospices civils de Lyon, groupement hospitalier Est, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Bron, France.
Transfus Clin Biol. 2011 Apr;18(2):262-8. doi: 10.1016/j.tracli.2011.02.004. Epub 2011 Mar 25.
Newborns and particularly preterm infants are a population at high risk of transfusion. The implementation of strategies to prevent transfusion by reducing blood loss, use of recombinant human erythropoietin, administration of iron and vitamins and delayed umbilical cord clamping have reduced the frequency of transfusions neonatal periods. The emergence of more stringent recommendations on indications for transfusion has been involved in this development. Various transformations and qualifications for red cell concentrates, platelet concentrates and fresh frozen plasma must be known to better adapt the blood products to newborn term and preterm according to their pathologies. Preparing pediatric units from a single donor for repeated transfusions reduces the allo-immune and infectious risks.
新生儿尤其是早产儿是输血的高危人群。通过减少失血、使用重组人促红细胞生成素、补充铁和维生素以及延迟脐带结扎来预防输血的策略实施,已降低了新生儿期输血的频率。对输血指征更严格建议的出现也参与了这一发展过程。必须了解红细胞浓缩物、血小板浓缩物和新鲜冰冻血浆的各种转化和特性,以便根据新生儿足月儿和早产儿的病情更好地使血液制品与之适配。为重复输血准备来自单一供体的儿科单位可降低同种免疫和感染风险。