Naimark B J, Tate R B, Manfreda J, Stephens N L, Mymin D
Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg.
Can J Cardiol. 1990 Sep;6(7):267-73.
The relationship between atrial and ventricular electrocardiographic abnormalities and exercise systolic blood pressure was studied in 246 male and 183 female subjects, of whom 199 males and 158 females were normotensive (resting blood pressure below 140/90 mmHg) and 47 males and 25 females were borderline hypertensive (resting systolic blood pressure 140 to 159 and/or diastolic blood pressure 90 to 99 mmHg). Subjects were classified into three groups according to systolic blood pressure during treadmill exercise (less than or equal to 180 mmHg, 180 to 199 mmHg and greater than or equal to 200 mmHg). With respect to atrial electrocardiographic abnormalities, the prevalence of abnormal values of the P-terminal force in lead V1 increased significantly with increased levels of resting exercise systolic blood pressure in males and females. The prevalence of electrocardiographic left ventricular hypertrophy, as reflected in abnormal values of one or more RS voltage indices, increased significantly with exercise systolic blood pressure in males but not in females. Males did not show a trend of increasing electrocardiographic left ventricular hypertrophy with increased resting systolic blood pressure means. In females, the significant difference between resting systolic blood pressure means and electrocardiographic left ventricular hypertrophy did not reflect a linear progression across resting systolic blood pressure categories. The significant association of the P-terminal force in lead V1 with exercise systolic blood pressure has not previously been reported. Although an association between left ventricular hypertrophy and exercise systolic blood pressure in hypertensives has been reported by others, the association seen in normotensive and borderline hypertensive males has not been reported previously.(ABSTRACT TRUNCATED AT 250 WORDS)
在246名男性和183名女性受试者中研究了心房和心室心电图异常与运动收缩压之间的关系,其中199名男性和158名女性血压正常(静息血压低于140/90 mmHg),47名男性和25名女性为临界高血压(静息收缩压140至159和/或舒张压90至99 mmHg)。根据跑步机运动期间的收缩压将受试者分为三组(小于或等于180 mmHg、180至199 mmHg和大于或等于200 mmHg)。关于心房心电图异常,男性和女性中V1导联P波终末电势异常值的患病率随静息运动收缩压水平的升高而显著增加。反映在一个或多个RS电压指数异常值中的心电图左心室肥厚患病率在男性中随运动收缩压显著增加,而在女性中则不然。男性并未表现出随着静息收缩压平均值升高心电图左心室肥厚增加的趋势。在女性中,静息收缩压平均值与心电图左心室肥厚之间的显著差异并未反映出跨静息收缩压类别呈线性进展。V1导联P波终末电势与运动收缩压之间的显著关联此前未见报道。尽管其他人已报道高血压患者左心室肥厚与运动收缩压之间存在关联,但血压正常和临界高血压男性中的这种关联此前未见报道。(摘要截短至250字)