Solomon Michael, Austin Kirk, Lee Peter, Holm Torbjørn, Rasmussen Peter Chr
Royal Prince Alfred Hospital, Sydney, Australien.
Ugeskr Laeger. 2011 Apr 4;173(14):1047-9.
Local recurrence (LR) still occurs in 5-10% of patients after surgery for a primary rectal cancer and is a major clinical problem, due to severe symptoms and poor survival. Patients with LR must be staged with regard to local tumour extension and distant disease. Magnetic resonance imaging and positron emission tomography-computed tomography are currently used for these purposes. A complete resection often implies a pelvic exenteration. The postoperative complication rate is high and therefore the patients must be carefully selected and counseled before surgery. If a R0 resection the prognosis is good with a 5-year survival about 55%.
原发性直肠癌手术后，仍有5%-10%的患者会出现局部复发（LR），这是一个主要的临床问题，因为症状严重且生存率低。LR患者必须根据局部肿瘤扩展和远处疾病进行分期。目前，磁共振成像和正电子发射断层扫描-计算机断层扫描用于这些目的。完整切除通常意味着盆腔脏器清除术。术后并发症发生率高，因此手术前必须仔细挑选患者并给予咨询。如果能实现R0切除，预后良好，5年生存率约为55%。
