Département d’Evaluation et Traitement de la Douleur Médecine Palliative, Pôle Neurosciences Cliniques, CHU de Nice-Hôpital Pasteur, 30 Avenue de la Voie Romaine, Nice cedex 1, France.
Cephalalgia. 2011 May;31(7):837-50. doi: 10.1177/0333102411398400. Epub 2011 Apr 4.
To evaluate the evidence for quality of life (QoL) impairment, disability, healthcare resource use and economic burden associated with chronic daily headache (CDH), focusing on chronic migraine (CM) with or without medication overuse.
A systematic review and qualitative synthesis of studies of patients/subjects with CDH that included CM, occurring on at least 15 days per month.
Thirty-four studies were included for review (25 studies of patients and nine of subjects from the general population). CDH and CDH with medication overuse headache (MOH) were consistently associated with a lower QoL compared to control or episodic headache (EH) and CDH without MOH. CDH was consistently associated with greater disability and productivity loss, more consultations, more or longer hospitalizations and higher direct costs than EH. Data were not amenable to statistical pooling.
The findings of this review underline the detriment to QoL and the disabling nature of CDH, and in particular CM and CDH with MOH, and negative impact on workplace productivity compared to other types of headache.
评估慢性每日头痛（CDH），尤其是慢性偏头痛（CM）伴或不伴药物过度使用相关的生活质量（QoL）受损、残疾、医疗资源使用和经济负担的证据。
对包括 CM 在内的 CDH 患者/受试者研究进行系统回顾和定性综合，这些研究的头痛每月至少发生 15 天。
共纳入 34 项研究进行综述（25 项患者研究和 9 项来自普通人群的受试者研究）。与对照或发作性头痛（EH）和无药物过度使用性头痛（MOH）的 CDH 相比，CDH 和伴有 MOH 的 CDH 始终与较低的 QoL 相关。与 EH 相比，CDH 始终与更大的残疾和生产力损失、更多的就诊次数、更多或更长时间的住院治疗以及更高的直接成本相关。数据不适于进行统计学汇总。
本综述的研究结果强调了 QoL 的损害和 CDH 的致残性质，特别是 CM 和伴有 MOH 的 CDH，以及与其他类型头痛相比对工作场所生产力的负面影响。
