Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, Greece.
Ann Acad Med Singap. 2011 Feb;40(2):80-3.
Peritoneal washing cytology and imprint cytology of pelvic lymph nodes samples were used to evaluate the rapid cytologic detection of peritoneal and retroperitoneal spread of endometrial cancer.
We undertook a study on 194 endometrial cancer patients who underwent primary treatment in the Gynecologic Clinic, Democritus University of Thrace. All patients were subjected to peritoneal washing (PW) cytology and imprint cytology performed on lymph node sampling. The cytologic specimens were stained by May-Grünwald Giemsa (MGG) and Haematoxylin eosin (HE) techniques. Cell-blocks prepared from peritoneal washings (PWs) and the lymph node samples were sent for histologic examination. The cytologic fi ndings were correlated to histologic results.
Rapid intraoperative cytology provides a useful diagnostic technique for the assessment of endometrial cancer spread. HE and MGG stain presented different values of sensitivity and specifi city in the detection of peritoneal and retroperitoneal spread of endometrial cancer.
Cytologic assessment of intraperitoneal and retroperitoneal spread of endometrial cancer is a rapid, intraoperative procedure, which provides the surgeon with useful information regarding the stage of the disease and the subsequent therapeutic approach.
我们采用腹腔冲洗液细胞学和盆腔淋巴结印片细胞学检查,旨在快速评估子宫内膜癌腹膜和腹膜后播散情况。
我们对 194 名在色雷斯德谟克利特大学附属医院妇科接受初次治疗的子宫内膜癌患者进行了一项研究。所有患者均接受腹腔冲洗液(PW)细胞学检查和淋巴结取样印片细胞学检查。细胞学标本用迈-格吉染色(MGG)和苏木精-伊红(HE)技术染色。从腹腔冲洗液(PW)和淋巴结样本中制备细胞块,用于组织学检查。细胞学结果与组织学结果相关联。
快速术中细胞学检查为评估子宫内膜癌播散提供了一种有用的诊断技术。HE 和 MGG 染色在检测子宫内膜癌腹膜和腹膜后播散方面具有不同的敏感性和特异性。
对子宫内膜癌腹腔和腹膜后播散的细胞学评估是一种快速的术中操作,可为外科医生提供有关疾病分期和后续治疗方法的有用信息。