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不明病因性蛛网膜下腔出血的长期预后。

Long term outcome after subarachnoid haemorrhage of unknown aetiology.

机构信息

Tampere University Hospital, Department of Neurosurgery, P O Box 2000, Tampere FIN-33521, Finland.

出版信息

J Neurol Neurosurg Psychiatry. 2011 Nov;82(11):1264-6. doi: 10.1136/jnnp.2010.239335. Epub 2011 Apr 6.

Abstract

BACKGROUND AND PURPOSE

The aim of this study was to assess the long term outcome after non-aneurysmal subarachnoid haemorrhage (SAH).

METHODS

1154 patients with SAH were treated in our hospital between 1989 and 1999. From this patient population, 97 patients had a non-aneurysmal SAH. All hospital records and death certificates were studied and 33 patients were examined by MRI and MR angiography more than 9 years (mean 12 years) after the initial bleeding.

RESULTS

The cohort consisted of 97 patients. Mean follow-up time was 9 years (range 0-19). During the follow-up period, 13 patients (13%) died. Four (4%) died from the initial bleeding less than 5 weeks after the initial haemorrhage. There was no delayed mortality due to SAH or subsequent bleedings. MR angiography revealed no new findings in 33 surviving patients.

CONCLUSIONS

Excess mortality during the first year after SAH was higher than 4%, and remained thereafter comparable with the general population. There were no rebleedings and MR imaging did not reveal any vascular pathology that could explain the earlier SAH.

摘要

背景与目的

本研究旨在评估非动脉瘤性蛛网膜下腔出血(SAH)的长期预后。

方法

1989 年至 1999 年期间,我院共收治了 1154 例 SAH 患者,其中 97 例为非动脉瘤性 SAH。对所有住院记录和死亡证明进行了研究,对 33 例患者进行了 MRI 和磁共振血管造影检查,时间超过初始出血后 9 年(平均 12 年)。

结果

本队列包括 97 例患者。平均随访时间为 9 年(范围 0-19 年)。随访期间,13 例患者(13%)死亡。4 例(4%)患者在初始出血后不到 5 周因初始出血死亡。无因 SAH 或后续出血导致的迟发性死亡。33 例存活患者的磁共振血管造影无新发发现。

结论

SAH 后第一年的超额死亡率高于 4%,此后与普通人群相当。无再出血,磁共振成像未发现任何可解释早期 SAH 的血管病理学变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ba2/3188783/07341641d60d/jnnp239335fig1.jpg

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