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蜱传病原体(蜱传脑炎和莱姆病)的传播与循环以及环境变化的作用

[Transmission and circulation of tick borne pathogens (TBE and Lyme borreliosis) and the role of changing environment].

作者信息

Zajkowska Joanna M

机构信息

Klinika Chorób Zakaźnych i Neuroinfekcji, Uniwersytet Medyczny w Białymstoku.

出版信息

Przegl Epidemiol. 2010;64(4):525-31.

Abstract

Ixodes ricinus is regarded as a species with great medical and veterinary meaning. Transmission of tick borne pathogens in mammals depends not only on systemic infection. Transmission of B. burgdorferi and tick-borne encephalitis virus in an infected organism differs, because of different location in tick, the differences in dissemination of the virus and bacteria (own motility) as well as mechanisms supporting bacterial infection. The mechanisms governing the transmission of these pathogens in nature have epidemiological importance and are essential in understanding the pathogenesis of diseases. The increase in the incidence of tick-borne encephalitis in recent years, is a marker of tick borne diseases. In the 90s, the number of cases among humans in many European countries remains at a higher level compared to the eighties. Similar observations consider to Lyme borreliosis. Natural environmental changes, mainly related to climate, as well as regional and local changes in distribution of the small rodents species, wild animals, anthropogenic factors (reforestation, drainage of swamps, increasing the reservoir of animals), and social change (increased human activities in forests, vaccinations) may have a significant impact on rates of tick-borne diseases.

摘要

蓖麻硬蜱被视为一种具有重大医学和兽医学意义的物种。蜱传播的病原体在哺乳动物中的传播不仅取决于全身感染。伯氏疏螺旋体和蜱传脑炎病毒在受感染生物体中的传播情况有所不同,这是由于它们在蜱体内的位置不同、病毒和细菌传播方式的差异(自身运动性)以及支持细菌感染的机制不同。这些病原体在自然界中的传播机制具有流行病学重要性,对于理解疾病的发病机制至关重要。近年来蜱传脑炎发病率的上升是蜱传疾病的一个标志。在20世纪90年代,许多欧洲国家人类病例数与80年代相比仍处于较高水平。莱姆病也有类似的观察结果。自然环境变化,主要与气候有关,以及小型啮齿动物物种、野生动物分布的区域和局部变化、人为因素(重新造林、沼泽排水、动物宿主增加)和社会变化(人类在森林中的活动增加、接种疫苗)可能对蜱传疾病的发病率产生重大影响。

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