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[角膜穿孔治疗中构造性表层角膜成形术的结果]

[Results of tectonic epikeratoplasty in the management of corneal perforations].

作者信息

Machowicz-Matejko Eulalia, Rakowska Ewa, Zagórski Zbigniew

机构信息

Z Kliniki Okulistyki Uniwersytetu Medycznego w Lublinie.

出版信息

Klin Oczna. 2010;112(10-12):296-300.

Abstract

PURPOSE

To present therapeutic application of tectonic epikeratoplasty as logical patch in severe ocular surface disorders.

MATERIAL AND METHODS

Full thickness corneo-scleral transplants, 14 mm in diameter were used in 67 operations of 41 patients with corneal perforation or descemetocele. (14 women and 27 men), in the period 1998-2008. The mean age of patients was 55.2 +/- 17.7 years (range 15-82). The transplants were sutured over the limbus or the scleral rim and was implanted under the conjunctiva after 360 degrees peritomy. Donor tissue unsuitable for penetrating keratoplasty because of poor endothelium or corneal scarring, was obtained from Lublin Eye Bank.

RESULTS

We observed closing of the perforation in all cases. Healing of the ulceration with scar formation and new vessels ingrowth was noted. In some eyes repeated epikeratoplasties were performed.

CONCLUSIONS

Tectonic epikeratoplasty is a safe and simple method of treatment of corneal perforations. It provides a biological patch stimulating the healing of corneal defects. It gives time for systemic treatment before further ocular surface reconstructive procedures can be performed.

摘要

目的

介绍结构性角膜表层移植术作为严重眼表疾病合理修补方法的治疗应用。

材料与方法

1998年至2008年期间,对41例角膜穿孔或后弹力层膨出患者(14名女性和27名男性)进行了67次手术,使用直径14毫米的全层角巩膜移植片。患者平均年龄为55.2±17.7岁(范围15 - 82岁)。移植片缝合于角膜缘或巩膜缘,在360度球结膜切开术后植入结膜下。供体组织因内皮功能不良或角膜瘢痕而不适用于穿透性角膜移植术,取自卢布林眼库。

结果

我们观察到所有病例的穿孔均闭合。注意到溃疡愈合伴有瘢痕形成和新生血管长入。部分眼进行了重复的角膜表层移植术。

结论

结构性角膜表层移植术是治疗角膜穿孔的一种安全、简单的方法。它提供了一个生物性修补片,刺激角膜缺损的愈合。在能够进行进一步的眼表重建手术之前,它为全身治疗争取了时间。

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