Reents W, Froehner S, Diegeler A, Urbanski P P
Department of Cardiovascular Surgery, Cardiovascular Clinic Bad Neustadt, Bad Neustadt, Germany.
Thorac Cardiovasc Surg. 2012 Apr;60(3):210-4. doi: 10.1055/s-0030-1270942. Epub 2011 Apr 7.
The appropriate approach for aortic coarctation associated with other cardiac diseases necessitating surgery is still controversial. The aim of this study was to evaluate the results after simultaneous surgery performed via median sternotomy and consisting of extra-anatomical ascending-to-descending aortic bypass and various other cardiac procedures.
Between January 1999 and February 2009, 13 consecutive patients with aortic coarctation coexistent with other cardiac diseases necessitating surgery underwent simultaneous surgery via median sternotomy. An extra-anatomical ascending-to-descending aortic bypass for coarctation repair was performed in all patients accompanied by various cardiac procedures (5 aortic root and valve replacement; 2 aortic valve replacement; 2 coronary artery bypass grafting; 2 mitral valve repair; 1 aortic valve replacement and coronary artery bypass grafting; 1 mitral and tricuspid valve repair). There were 3 women and 10 men with a mean age of 52 years (range 25-69). Two patients had recurrent or residual coarctation 37 and 46 years after previous surgical repair, respectively.
Early mortality was 0 and there was only 1 late death during the follow-up of up to 11 years. New York Heart Association (NYHA) functional class improved on average from 2.4 to 1.2. At the last follow-up, blood pressure measured at the upper and lower extremities showed no gradient in any patient, indicating a durable function of the extra-anatomical bypass. Only 3 patients were on reduced antihypertensive therapy; 8 patients were on the same medication and 1 patient required increased medication therapy compared with the medication prior to surgery.
Ascending-to-descending bypass can be performed via median sternotomy simultaneously with various cardiac procedures without considerable extension of the procedure. The operative and long-term results are excellent, and this approach can be recommended as the procedure of choice in patients with aortic coarctation and additional cardiac diseases necessitating surgery.
对于合并其他需要手术治疗的心脏疾病的主动脉缩窄,合适的治疗方法仍存在争议。本研究的目的是评估经正中胸骨切开术同期进行的手术效果,该手术包括非解剖性升主动脉至降主动脉旁路移植术及各种其他心脏手术。
1999年1月至2009年2月,13例连续的合并其他需要手术治疗的心脏疾病的主动脉缩窄患者经正中胸骨切开术同期进行手术。所有患者均进行了非解剖性升主动脉至降主动脉旁路移植术以修复缩窄,并同期进行了各种心脏手术(5例主动脉根部及瓣膜置换术;2例主动脉瓣置换术;2例冠状动脉旁路移植术;2例二尖瓣修复术;1例主动脉瓣置换术及冠状动脉旁路移植术;1例二尖瓣及三尖瓣修复术)。患者中3例女性,10例男性,平均年龄52岁(范围25 - 69岁)。2例患者分别在先前手术修复后37年和46年出现复发性或残留性缩窄。
早期死亡率为0,在长达11年的随访期内仅有1例晚期死亡。纽约心脏协会(NYHA)心功能分级平均从2.4改善至1.2。在最后一次随访时,所有患者上下肢血压均无压差,表明非解剖性旁路功能持久。与术前用药相比,只有3例患者减少了降压治疗;8例患者用药不变,1例患者需要增加药物治疗。
经正中胸骨切开术可同期进行升主动脉至降主动脉旁路移植术及各种心脏手术,而无需显著延长手术时间。手术及长期效果良好,对于合并其他需要手术治疗的心脏疾病的主动脉缩窄患者,该方法可作为首选推荐。