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[促甲状腺素释放激素治疗脑血管疾病]

[Protirelin in the treatment of cerebrovascular disorders].

作者信息

Costa R, Cirrincione M, Chinnici M, Scaffidi A

机构信息

Cattedra di Fisiopatologia Medica, Università degli Studi di Palermo.

出版信息

Clin Ter. 1990;134(3-4):205-9.

PMID:2147622
Abstract

Effects of protirelin tartrate, administered for 14 days (2 mg/day, i.m.) to 15 patients with acute cerebrovascular disease have been investigated. The evaluation was performed by means of SPECT, at enrollment and at the end of treatment. This evaluation was aimed at the early detection of ischemic damage and assessment of the size of the hypoperfusion area. Treatment with protirelin tartrate was well tolerated and led to definite improvement of the scintigraphic findings in about 74% of the patients.

摘要

研究了对15例急性脑血管疾病患者连续14天(每天2毫克,肌肉注射)给予酒石酸普罗瑞林的效果。在入组时和治疗结束时通过单光子发射计算机断层扫描(SPECT)进行评估。该评估旨在早期检测缺血性损伤并评估低灌注区域的大小。酒石酸普罗瑞林治疗耐受性良好,约74%的患者闪烁扫描结果有明显改善。

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