Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Neurol India. 2011 Mar-Apr;59(2):266-9. doi: 10.4103/0028-3886.79143.
A "Hot Cross Bun" sign on T2-weighted MRI was described as a result of selective loss of myelinated transverse pontocerebellar fibers and neurons in the pontine raphe with preservation of the pontine tegmentum and corticospinal tracts (CST). However, neuropathologic studies showed contradicting results with no sparing of the CST. This is a pictorial and quantitative demonstration of the sign on diffusion tensor imaging and tractography, which provides the imaging evidence that is consistent with neuropathologic findings.
T2 加权 MRI 上的“十字面包”征是由于选择性地丧失了桥脑被盖的有髓横向桥小脑纤维和神经元，而桥脑被盖和皮质脊髓束（CST）得以保留。然而，神经病理学研究结果显示 CST 并没有得到保留，这与上述描述结果相矛盾。本研究通过弥散张量成像和轨迹成像对该征象进行了直观和定量的展示，为与神经病理学发现一致的影像学证据提供了支持。
