葡萄膜炎性青光眼的手术治疗结果
Surgical outcomes of uveitic glaucoma.
作者信息
Carreño Ester, Villarón Sonia, Portero Alejandro, Herreras José M, Maquet José A, Calonge Margarita
机构信息
Ocular Immunology Unit-IOBA (Instituto Universitario de Oftalmobiología), University of Valladolid, Campus Miguel Delibes, Camino del Cementerio s/n, 47011, Valladolid, Spain,
出版信息
J Ophthalmic Inflamm Infect. 2011 Jun;1(2):43-53. doi: 10.1007/s12348-010-0012-8. Epub 2010 Nov 18.
PURPOSE
Secondary glaucoma is a difficult and frequent complication of uveitis. The aim of this study is to describe the results of surgery in uveitic glaucoma and to identify situations linked to a high risk of failure of the surgery.
METHODS
Retrospective observational study. Clinical and surgical data from 27 cases of uveitic glaucoma that underwent glaucoma surgery over a period of 9 years were collected.
RESULTS
The main diagnosis and aetiology were anterior uveitis (61.90%) and herpes (38.10%) respectively. Trabeculectomy with mitomycin C was performed in 51.9% of the cases. An intraocular pressure lower than 16 mmHg and managed with less than two drugs was achieved in 48.15% of the cases. Higher risks of surgical failure were associated with intermediate uveitis, idiopathic uveitis, Fuchs' cyclitis, combined surgery with phacoemulsification, omission of mitomycin C, intraocular inflammation at surgery and relapse of the uveitis.
CONCLUSIONS
There are some situations linked to a high risk of failure of surgery in uveitic glaucoma, which should be avoided when possible, mainly the association of higher risk with combined approaches.
目的
继发性青光眼是葡萄膜炎常见且棘手的并发症。本研究旨在描述葡萄膜炎性青光眼的手术结果，并确定与手术高失败风险相关的情况。
方法
回顾性观察研究。收集了9年间27例接受青光眼手术的葡萄膜炎性青光眼患者的临床和手术数据。
结果
主要诊断及病因分别为前葡萄膜炎（61.90%）和疱疹（38.10%）。51.9%的病例行丝裂霉素C小梁切除术。48.15%的病例眼压低于16 mmHg且使用药物少于两种。手术失败风险较高与中间葡萄膜炎、特发性葡萄膜炎、富克斯环形睫状体炎、联合白内障超声乳化手术、未使用丝裂霉素C、手术时眼内炎症及葡萄膜炎复发有关。
结论
葡萄膜炎性青光眼存在一些与手术高失败风险相关的情况，应尽可能避免，主要是高风险与联合手术方式相关。
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