The University of Queensland, Centre for Burden of Disease & Cost Effectiveness, School of Population Health, Brisbane, Australia.
Inj Prev. 2011 Dec;17(6):365-70. doi: 10.1136/ip.2010.029579. Epub 2011 Apr 12.
To determine the proportion of hip fracture patients who experience long-term disability and to re-estimate the resulting burden of disease associated with hip fractures in Australia in 2003.
A literature review of the functional outcome following a hip fracture (keywords: morbidity, treatment outcome, disability, quality of life, recovery of function, hip fractures, and femoral neck fractures) was carried out using PubMed and Ovid MEDLINE.
A range of scales and outcome measures are used to evaluate recovery following a hip fracture. Based on the available evidence on restrictions in activities of daily living, 29% of hip fracture cases in the elderly do not reach their pre-fracture levels 1 year post-fracture. Those who do recover tend to reach their pre-fracture levels of functioning at around 6 months. These new assumptions result in 8251 years lived with disability for hip fractures in Australia in 2003, a 4.5-fold increase compared with the previous calculation based on Global Burden of Disease assumptions that only 5% of hip fractures lead to long-term disability and that the duration of short-term disability is just 51 days.
The original assumptions used in burden of disease studies grossly underestimate the long-term disability from hip fractures. The long-term consequences of other injuries may similarly have been underestimated and need to be re-examined. This has important implications for modelling the cost-effectiveness of preventive interventions where disability-adjusted life years are used as a measure of health outcome.
确定长期残疾的髋部骨折患者的比例,并重新估计 2003 年澳大利亚髋部骨折相关疾病负担。
使用 PubMed 和 Ovid MEDLINE 对髋部骨折后功能结果(关键词:发病率、治疗结果、残疾、生活质量、功能恢复、髋部骨折和股骨颈骨折)进行文献回顾。
各种量表和结果测量方法用于评估髋部骨折后的恢复情况。根据日常生活活动受限的现有证据,29%的老年髋部骨折患者在骨折后 1 年无法达到骨折前的水平。那些能够恢复的患者往往在 6 个月左右达到骨折前的功能水平。这些新的假设导致 2003 年澳大利亚髋部骨折导致残疾的 8251 年生命年,与之前基于全球疾病负担假设的计算相比增加了 4.5 倍,之前的假设仅认为 5%的髋部骨折导致长期残疾,且短期残疾的持续时间仅为 51 天。
疾病负担研究中使用的原始假设严重低估了髋部骨折的长期残疾。其他损伤的长期后果可能也被低估了,需要重新审查。这对使用残疾调整生命年来衡量健康结果的预防干预措施的成本效益建模具有重要意义。