Vaney C
Neurologische Rehabilitations- und MS-Station, Bernische Höhenklinik Bellevue, Montana.
Schweiz Med Wochenschr. 1990 Dec 29;120(51-52):1959-64.
Although pain is not considered a typical symptom of multiple sclerosis, more than 50% of patients with MS present with pain syndromes. In the setting of an incurable disease, symptom control and particularly pain control is very important in achieving a better quality of life. For paroxysmal pain syndromes such as trigeminal neuralgia or painful tonic seizures, carbamazepine and other anticonvulsive drugs are the cornerstone of treatment. On the other hand, drugs are not always effective in treating the various chronic pain syndromes such as dysesthetic extremity pain or leg spasms. In these conditions, individualized regular physiotherapy may relieve pain.
虽然疼痛并非多发性硬化症的典型症状,但超过50%的多发性硬化症患者存在疼痛综合征。在这种无法治愈的疾病背景下,症状控制尤其是疼痛控制对于提高生活质量非常重要。对于三叉神经痛或痛性强直性发作等阵发性疼痛综合征,卡马西平和其他抗惊厥药物是治疗的基石。另一方面,药物在治疗各种慢性疼痛综合征(如感觉异常性肢体疼痛或腿部痉挛)时并不总是有效。在这些情况下,个体化的定期物理治疗可能会缓解疼痛。