Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan.
Psychiatry Clin Neurosci. 2011 Jun;65(4):384-5. doi: 10.1111/j.1440-1819.2011.02211.x. Epub 2011 Apr 14.
Discontinuation symptoms can follow the stoppage of almost all classes of antidepressants, including selective serotonin reuptake inhibitors. We report two cases suffering from visual and auditory hallucinations: Case 1 abruptly stopped taking paroxetine (20 mg/day), and Case 2 discontinued paroxetine after reducing the dose from 20 mg/day to 10 mg/day for 5 months. Both cases experienced visual and auditory hallucinations in addition to dizziness, headache, insomnia, and nausea a couple of days after paroxetine discontinuation. These observations suggest that hallucinations are a part of the discontinuation syndrome that results from paroxetine discontinuation. Physicians should be aware of this symptom.
停药症状可能会出现在几乎所有类别的抗抑郁药停药后，包括选择性 5-羟色胺再摄取抑制剂。我们报告了两例出现视幻觉和听幻觉的病例：病例 1 突然停止服用帕罗西汀（20mg/天），病例 2 在服用帕罗西汀 5 个月后将剂量从 20mg/天减少至 10mg/天，随后出现视幻觉和听幻觉，同时伴有头晕、头痛、失眠和恶心。这两例患者在帕罗西汀停药后几天内均出现上述症状。这些观察结果表明，幻觉是帕罗西汀停药后出现的停药综合征的一部分。医生应注意这种症状。
