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圆锥角膜穿透性角膜移植术后20年角膜移植片上的萨尔茨曼结节性变性

[Salzmann's nodular degeneration on a corneal graft 20 years after penetrating keratoplasty for keratoconus].

作者信息

Gatzioufas Z, Hager T, El-Husseiny M, Kozeis N, Seitz B

机构信息

Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 22, 66421 Homburg/Saar.

出版信息

Ophthalmologe. 2011 Oct;108(10):963-5. doi: 10.1007/s00347-011-2361-6.

Abstract

INTRODUCTION

We report a unique case of a young patient who underwent penetrating keratoplasty for keratoconus 20 years previously and presented in our department with visual deterioration due to Salzmann's nodular degeneration (SND) on the corneal graft, induced probably by underlying recurrent herpetic (HSV) keratitis. The patient was treated with phototherapeutic keratectomy (PTK) and despite the low endothelial density of the corneal graft, visual acuity was sufficiently restored.

CONCLUSION

Treatment with PTK is a promising therapeutic option in SND to avoid repeat penetrating keratoplasty, even if the prognosis for the corneal graft is endangered by several risk factors (age of the graft, low endothelial density, subclinical recurrent HSV infection).

摘要

引言

我们报告了一例独特的病例,一名年轻患者20年前因圆锥角膜接受了穿透性角膜移植术,现因角膜移植片上的萨尔茨曼结节性变性(SND)导致视力下降前来我院就诊,可能是由潜在的复发性疱疹性(HSV)角膜炎引起的。该患者接受了光动力角膜切削术(PTK)治疗,尽管角膜移植片的内皮细胞密度较低,但视力仍得到了充分恢复。

结论

对于SND,PTK治疗是一种有前景的治疗选择,可避免再次进行穿透性角膜移植术,即使角膜移植片的预后受到多种危险因素(移植片年龄、低内皮细胞密度、亚临床复发性HSV感染)的威胁。

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