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减少青少年鼻咽血管纤维瘤的术中出血。

Reducing intraoperative bleeding of juvenile nasopharyngeal angiofibroma.

机构信息

Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

World Neurosurg. 2010 Oct-Nov;74(4-5):497-500. doi: 10.1016/j.wneu.2010.06.048. Epub 2011 Jan 12.

Abstract

OBJECTIVE

To report the case of a young patient with juvenile nasopharyngeal angiofibroma (JNA) (Fisch grade IVb) operated on in a semisitting position.

METHODS

A 17-year-old boy complained of nasal obstruction and pain in the left periorbital area in April 2007. Magnetic resonance imaging (MRI) showed grade IVb JNA with invasion of the anterior cranial fossa, the cavernous sinuses, and the chiasm. Resections of the tumor through bifrontal craniotomy in June 2007 and through lateral rhinotomy in January 2008, both performed in the supine position, were complicated by excessive bleeding.

RESULTS

In February 2008, the lesion was removed through a transfacial approach in a semisitting position after transnasal and percutaneous embolization. The vascular support to the tumor was reduced by using high-power bipolar forceps, monopolar diathermy, and intratumoral injection of fibrin glue. The main part of the lesion was successfully removed.

CONCLUSIONS

The combination of preoperative embolization (transnasal, percutaneous, endovascular), semisitting positioning of the patient, intraoperative injection of fibrin glue, and high-power bipolar forceps and monopolar diathermy is helpful in reducing surgical bleeding and enabling safe resection of JNA.

摘要

目的

报告 1 例采用半坐体位行手术治疗的青少年鼻咽血管纤维瘤(JNA)(Fisch 分级 IVb 级)患者。

方法

17 岁男性,因鼻塞和左眼周疼痛于 2007 年 4 月就诊。磁共振成像(MRI)显示 IVb 级 JNA,肿瘤侵犯颅前窝、海绵窦和视交叉。2007 年 6 月采用额部双额开颅和 2008 年 1 月经鼻侧切开均在仰卧位下进行肿瘤切除术,均因过度出血而复杂化。

结果

2008 年 2 月,在经鼻和经皮栓塞后,采用经面中部入路在半坐体位下切除病变。采用高功率双极电凝镊、单极电凝和肿瘤内注射纤维蛋白胶减少肿瘤的血管支持,成功切除了病变的主要部分。

结论

术前栓塞(经鼻、经皮、血管内)、患者半坐体位、术中纤维蛋白胶注射以及高功率双极电凝镊和单极电凝的联合应用有助于减少手术出血,实现 JNA 的安全切除。

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