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单阶段改良悬雍垂腭咽成形术联合鼻手术治疗成人阻塞性睡眠呼吸暂停低通气综合征的疗效。

Efficacy of single-staged modified uvulopalatopharyngoplasty with nasal surgery in adults with obstructive sleep apnea syndrome.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.

出版信息

Otolaryngol Head Neck Surg. 2011 Jun;144(6):994-9. doi: 10.1177/0194599811398194. Epub 2011 Mar 1.

Abstract

OBJECTIVE

The aim of this study was to investigate the clinical efficacy of single-staged modified uvulopalatopharyngoplasty (UPPP) with nasal surgery and the relationship between its surgical outcomes and an anatomy-based staging system in patients with obstructive sleep apnea syndrome (OSAS) with nasal obstruction.

STUDY DESIGN AND SETTING

Before-after analysis at a university hospital.

SUBJECTS AND METHODS

A total of 41 consecutive OSAS patients (mean age 40.1 ± 7.3 years) who underwent single-staged modified (uvula-preserving) UPPP with nasal surgery were included. The investigators compared subjective symptoms and polysomnographic data before and after surgery and investigated objective surgical outcomes according to the anatomy-based (Friedman) staging system and postoperative complications. Surgical success was defined as a reduction of at least 50% in preoperative apnea-hypopnea index (AHI) and a postoperative AHI of less than 20 per hour.

RESULTS

After simultaneous nasal-oropharyngeal surgery, the AHI significantly decreased (from 45.9 ± 23.4 to 20.9 ± 22.1 events per hour; P < .001) and the overall success rate was 56.1% (23/41). Surgical success rates in stages I, II, and III were 70.6% (12/17), 60.0% (9/15), and 22.2% (2/9), respectively. There were no major complications during or after surgery, and most minor complications were transient and resolved without morbidity.

CONCLUSIONS

Single-staged modified UPPP with nasal surgery is an available and relatively safe surgical approach in OSAS patients with nasal obstruction. To achieve the best possible surgical outcomes, it is important to select appropriate patients using the anatomy-based staging system.

摘要

目的

本研究旨在探讨伴鼻腔阻塞的阻塞性睡眠呼吸暂停综合征(OSAS)患者行单阶段改良悬雍垂腭咽成形术(UPPP)联合鼻手术的临床疗效,及其与基于解剖学的分期系统之间的关系。

研究设计与设置

在一所大学医院进行的前后对照分析。

研究对象和方法

共纳入 41 例连续的伴鼻腔阻塞的 OSAS 患者(平均年龄 40.1±7.3 岁),行单阶段改良(保留悬雍垂)UPPP 联合鼻手术。研究者比较了手术前后的主观症状和多导睡眠图数据,并根据基于解剖学(Friedman)的分期系统和术后并发症来评估客观手术结果。手术成功定义为术前呼吸暂停低通气指数(AHI)降低至少 50%,术后 AHI 小于 20 次/小时。

结果

同期行鼻-口咽手术治疗后,AHI 明显降低(从 45.9±23.4 降至 20.9±22.1 次/小时;P<0.001),总体成功率为 56.1%(23/41)。Ⅰ期、Ⅱ期和Ⅲ期的手术成功率分别为 70.6%(12/17)、60.0%(9/15)和 22.2%(2/9)。手术期间或之后无重大并发症,大多数轻微并发症是短暂的,且无需治疗即可缓解。

结论

伴鼻腔阻塞的 OSAS 患者行单阶段改良 UPPP 联合鼻手术是一种可行且相对安全的手术方法。为了获得最佳的手术效果,使用基于解剖学的分期系统选择合适的患者非常重要。

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