Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
Expert Rev Hematol. 2011 Apr;4(2):161-71. doi: 10.1586/ehm.11.17.
Computed tomography (CT), (18)F-fluorodeoxyglucose (FDG)-PET and the hybrid FDG-PET/CT are the most commonly used diagnostic tools for the initial staging and treatment response assessment of malignant lymphomas. MRI techniques such as whole-body MRI and diffusion-weighted imaging may be good radiation-free alternatives to FDG-PET/CT, which may be particularly relevant for children. Diffusion-weighted imaging is characterized by high sensitivity for the detection of lesions and allows quantitative assessment of diffusion that may aid in the evaluation of malignant lymphomas. This article will review the value of these emerging MRI techniques for the staging and response assessment of malignant lymphoma. Furthermore, we will discuss some additional imaging techniques that are the subject of ongoing research and may have potential for future clinical application.
计算机断层扫描（CT）、（18）F-氟代脱氧葡萄糖（FDG）-正电子发射断层扫描（PET）以及 FDG-PET/CT 融合显像，是恶性淋巴瘤初始分期和治疗反应评估最常用的诊断工具。全身磁共振成像（MRI）和弥散加权成像等 MRI 技术可能是 FDG-PET/CT 的良好无辐射替代方法，对于儿童来说尤其相关。弥散加权成像具有检测病变的高灵敏度，并允许对扩散进行定量评估，这可能有助于恶性淋巴瘤的评估。本文将综述这些新兴 MRI 技术在恶性淋巴瘤分期和反应评估中的价值。此外，我们还将讨论一些正在研究中的其他成像技术，这些技术可能具有未来临床应用的潜力。
