Girón-Vallejo O, López-Gutiérrez J C, Fernández-Pineda I, Méndez N A, Ruiz Jiménez J I
Department of Pediatric Surgery, Virgen de la Arrixaca Children’s Hospital, Murcia, Spain.
Pediatr Dermatol. 2010 Nov-Dec;27(6):672-3. doi: 10.1111/j.1525-1470.2010.01336.x.
We report the case of an 18-month-old boy who presented with caries in the upper central incisors associated with the use of propranolol solution for the treatment of an infantile hemangioma. This side effect of propranolol solution has not been reported before, and it may result from a sucrose-based excipient of the solution, or decreased salivation caused by beta-adrenergic antagonist effect of propranolol.
我们报告了一例18个月大男孩的病例，该男孩因使用普萘洛尔溶液治疗婴儿血管瘤而出现上颌中切牙龋齿。普萘洛尔溶液的这种副作用此前未见报道，可能是由于该溶液中基于蔗糖的辅料，或普萘洛尔的β-肾上腺素能拮抗剂作用导致唾液分泌减少所致。
Zotero 插件