Ziu Tatjana, Ajvazi Halil
Department of Ophthalmology, Hospital Centre of Elbasan, Albany.
Oftalmologia. 2010;54(4):73-5.
Cogan syndrome-CS, is a rare autoimmune disease defined as an inflammation of the eyes followed by bilateral audiovestibular symptoms.
This is case report of S. A. male, born on April 18th 1986 from Elbasan, presented with the gastrointestinal, audiovestibulary and eyes disorders, weight loss and progressive fatigue. CT-scan showed an inflammation in lymph nodes in the right lower quadrant of his abdomen. MRI examination showed inner ear inflammation. Ophthalmologic examination revealed that patient was very sensitive to light and visual acuity was lowing 5/10 LE and 6/10 RE, a slit-lamp examination ascertained the interstitial keratitis, iritis and conjunctivitis.
Considering all diseases manifestations, the results of all examinations, a diagnose of CS was finally made. The treatment with steroids and immunosupresors showed an improvement of diseases but hearing loss was not reversed.
科根综合征(CS)是一种罕见的自身免疫性疾病,定义为眼部炎症后出现双侧听觉前庭症状。
这是一例来自爱尔巴桑的男性患者,出生于1986年4月18日,出现胃肠道、听觉前庭和眼部疾病、体重减轻及进行性疲劳。CT扫描显示其右下腹部淋巴结有炎症。MRI检查显示内耳炎症。眼科检查发现患者对光非常敏感,左眼视力降至5/10,右眼视力为6/10,裂隙灯检查确定存在间质性角膜炎、虹膜炎和结膜炎。
综合所有疾病表现及各项检查结果,最终诊断为CS。使用类固醇和免疫抑制剂治疗后疾病有所改善,但听力损失未得到逆转。