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[中国南方哮喘自我管理感知水平及影响因素调查]

[Investigation of the level of perceived control of asthma and the factors affecting such perception in South China].

作者信息

Lü Yan-Hua, Zhao Hai-Jin, Liu Lai-Yu, Cai Shao-Xi, Zhu Shun-Fang, Liang Zhen-Yu, Wu Yue-Xian

机构信息

Department of Respiratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2011 Apr;31(4):641-4.

Abstract

OBJECTIVE

To investigate the level of the patients perceived control of asthma (PCA) in South China and analyze the risk factors contributing to inadequate PCA.

METHODS

A total of 150 asthmatic out-patients consisting of 86 males and 64 females aged 19-65 (38.6∓11.7) years were enrolled in this investigation. The patients were asked to complete questionnaires of the demographic data, perceived control of asthma (PCAQ-6) scales, asthma control test (ACT) scales and Standard asthma-specific quality of life [AQLQ(S)] scale. The data of spirometric measurements, blood cell count and induced sputum cell count were also collected.

RESULTS

All the 150 asthmatic out-patients recruited completed the questionnaires and examinations. The PCAQ-6 scores ranged from 10 to 26 (18.75∓3.42) in these patients (18.6∓3.28 in male and 18.95∓3.6 in female patients), significantly lower than those reported in other countries (P<1). PCA was positively correlated to the level of asthma control (r(p)=0.377, P=0.000) and AQLQ(S) scores (r(p)=0.675, P=0.000). Multiple linear regression showed that PCA was positively correlated to FEV1% and blood neutrophil counts, and inversely to asthma duration.

CONCLUSION

The level of the PCA appears inadequate in South China. The PCA can affect the level of asthma control and asthma-specific quality of life. The factors contributing to inadequate PCA include primarily asthma duration, lung function and blood neutrophil counts.

摘要

目的

调查中国南方哮喘患者的哮喘自我感知控制(PCA)水平,并分析导致PCA不足的危险因素。

方法

本研究共纳入150例哮喘门诊患者,其中男性86例,女性64例,年龄19 - 65岁(38.6±11.7岁)。患者需完成人口统计学数据问卷、哮喘自我感知控制(PCAQ - 6)量表、哮喘控制测试(ACT)量表以及标准哮喘特异性生活质量[AQLQ(S)]量表。同时收集肺功能测量、血细胞计数和诱导痰细胞计数的数据。

结果

所有150例招募的哮喘门诊患者均完成了问卷和检查。这些患者的PCAQ - 6评分范围为10至26分(18.75±3.42)(男性为18.6±3.28,女性为18.95±3.6),显著低于其他国家报告的评分(P<1)。PCA与哮喘控制水平(r(p)=0.377,P = 0.000)和AQLQ(S)评分(r(p)=0.675,P = 0.000)呈正相关。多元线性回归显示,PCA与第一秒用力呼气容积百分比(FEV1%)和血液中性粒细胞计数呈正相关,与哮喘病程呈负相关。

结论

中国南方的PCA水平似乎不足。PCA可影响哮喘控制水平和哮喘特异性生活质量。导致PCA不足的因素主要包括哮喘病程、肺功能和血液中性粒细胞计数。

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