Lü Yan-Hua, Zhao Hai-Jin, Liu Lai-Yu, Cai Shao-Xi, Zhu Shun-Fang, Liang Zhen-Yu, Wu Yue-Xian
Department of Respiratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2011 Apr;31(4):641-4.
To investigate the level of the patients perceived control of asthma (PCA) in South China and analyze the risk factors contributing to inadequate PCA.
A total of 150 asthmatic out-patients consisting of 86 males and 64 females aged 19-65 (38.6∓11.7) years were enrolled in this investigation. The patients were asked to complete questionnaires of the demographic data, perceived control of asthma (PCAQ-6) scales, asthma control test (ACT) scales and Standard asthma-specific quality of life [AQLQ(S)] scale. The data of spirometric measurements, blood cell count and induced sputum cell count were also collected.
All the 150 asthmatic out-patients recruited completed the questionnaires and examinations. The PCAQ-6 scores ranged from 10 to 26 (18.75∓3.42) in these patients (18.6∓3.28 in male and 18.95∓3.6 in female patients), significantly lower than those reported in other countries (P<1). PCA was positively correlated to the level of asthma control (r(p)=0.377, P=0.000) and AQLQ(S) scores (r(p)=0.675, P=0.000). Multiple linear regression showed that PCA was positively correlated to FEV1% and blood neutrophil counts, and inversely to asthma duration.
The level of the PCA appears inadequate in South China. The PCA can affect the level of asthma control and asthma-specific quality of life. The factors contributing to inadequate PCA include primarily asthma duration, lung function and blood neutrophil counts.
调查中国南方哮喘患者的哮喘自我感知控制(PCA)水平,并分析导致PCA不足的危险因素。
本研究共纳入150例哮喘门诊患者,其中男性86例,女性64例,年龄19 - 65岁(38.6±11.7岁)。患者需完成人口统计学数据问卷、哮喘自我感知控制(PCAQ - 6)量表、哮喘控制测试(ACT)量表以及标准哮喘特异性生活质量[AQLQ(S)]量表。同时收集肺功能测量、血细胞计数和诱导痰细胞计数的数据。
所有150例招募的哮喘门诊患者均完成了问卷和检查。这些患者的PCAQ - 6评分范围为10至26分(18.75±3.42)(男性为18.6±3.28,女性为18.95±3.6),显著低于其他国家报告的评分(P<1)。PCA与哮喘控制水平(r(p)=0.377,P = 0.000)和AQLQ(S)评分(r(p)=0.675,P = 0.000)呈正相关。多元线性回归显示,PCA与第一秒用力呼气容积百分比(FEV1%)和血液中性粒细胞计数呈正相关,与哮喘病程呈负相关。
中国南方的PCA水平似乎不足。PCA可影响哮喘控制水平和哮喘特异性生活质量。导致PCA不足的因素主要包括哮喘病程、肺功能和血液中性粒细胞计数。