Department of Otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Laryngoscope. 2011 May;121(5):961-4. doi: 10.1002/lary.21459.
Amyloid goiter is an atypical presentation of an already rare disease, amyloidosis, which uncommonly comes across in previous review of literature. A patient presented with respiratory distress, which aroused a dilemma on diagnosis because the presentation mimicked that of malignancy. A high index of attentiveness should be kept whenever amyloid deposits are seen on fine needle aspiration cytology, as they are also established in medullary carcinoma. Amyloid deposits have been traced in goiter; however, it was astonishing to observe this condition causing a rapidly growing goiter, large enough to cause respiratory distress. The confirmative diagnosis rested on the histopathology of the specimen.
甲状腺淀粉样变是一种罕见疾病——淀粉样变性的非典型表现,在之前的文献回顾中很少见到。一名患者因呼吸窘迫就诊,这给诊断带来了困境,因为其表现类似于恶性肿瘤。在细针抽吸细胞学检查中发现淀粉样物质沉积时,应保持高度警惕,因为这种情况也存在于髓样癌中。甲状腺中也曾发现淀粉样物质沉积;然而,令人惊讶的是,这种情况会导致甲状腺迅速肿大,大到足以引起呼吸窘迫。明确的诊断取决于标本的组织病理学。