Mahmud N U, Hossain M A, Nahar K, Mahmud C, Paul S K, Ahmed S, Haque N, Kalam A, Parveen U S
Department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh.
Mymensingh Med J. 2011 Apr;20(2):187-91.
The genital chlamydial infection is the most common sexually transmitted diseases (STD) and major cause of infertility and ectopic pregnancy for millions of women in the world particularly in developing countries. This study was performed to find out the seroprevalence of Chlamydia trachomatis (CT) genital infection in women of reproductive age attending the Department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital (MMCH) during the period from January 2009 to December 2009 through a cross sectional study. A total of 108 serum samples from symptomatic and asymptomatic pregnant and non-pregnant women were tested for CT specific IgG antibody by Enzyme Linked Immunosorbent Assay (ELISA). A total of 31(28.7%) patients were found to have antibody of which 44% (26/59) were from pregnant group and 10.2% (5/49) from non-pregnant group. The seropositivity was 21.6% (16/74) in symptomatic cases and 44.1% (15/34) in asymptomatic cases. The study shows high prevalence of Chlamydial antibody which is common in pregnant and non-pregnant, symptomatic and asymptomatic adult women in Bangladesh. So, screening for chlamydial infection should be done routinely by suitable tests in sexually active symptomatic and asymptomatic women including pregnant women to prevent serious complications.
生殖道衣原体感染是最常见的性传播疾病(STD),也是全球数百万女性,尤其是发展中国家女性不孕和异位妊娠的主要原因。本研究通过横断面研究,旨在查明2009年1月至2009年12月期间在迈门辛医学院医院(MMCH)妇产科就诊的育龄妇女沙眼衣原体(CT)生殖道感染的血清流行率。通过酶联免疫吸附测定(ELISA)对108份有症状和无症状的孕妇及非孕妇血清样本进行CT特异性IgG抗体检测。共发现31例(28.7%)患者有抗体,其中4组(26/59)来自孕妇组,10.2%(5/49)来自非孕妇组。有症状病例的血清阳性率为21.6%(16/74),无症状病例为44.1%(15/34)。该研究表明衣原体抗体的高流行率在孟加拉国的孕妇和非孕妇、有症状和无症状成年女性中都很常见。因此,应通过适当检测对有性活动的有症状和无症状女性(包括孕妇)进行衣原体感染的常规筛查,以预防严重并发症。