Roberts Robert
Robert Roberts, Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada.
World J Cardiol. 2011 Apr 26;3(4):121-6. doi: 10.4330/wjc.v3.i4.121.
Dr. Robert Roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Centre along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine, Houston, Texas. His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genetics of cardiomyopathies. He is regarded as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert's laboratory and, in collaboration with the international consortium, CARDIoGRAM, has identified 13 novel genes for CAD.
罗伯特·罗伯茨博士现任医学教授、鲁迪加拿大心血管遗传学中心主任，同时担任渥太华大学心脏研究所所长兼首席执行官。在此任职之前，他在得克萨斯州休斯敦的贝勒医学院担任了23年的心脏病学主任。他最初的研究领域是心脏酶学，由此开发出了MBCK检测法，该检测法在30多年的时间里一直是心肌梗死的标准诊断方法。20世纪70年代末，他的研究兴趣转向分子生物学和心肌病遗传学。他被视为分子心脏病学的创始人之一，已经鉴定并测序了20多个导致心血管疾病的基因。在过去6年里，他开展了全基因组关联研究，以确定易患冠状动脉疾病（CAD）和心肌梗死的基因。CAD的首个遗传变异体9p21是由罗伯特博士的实验室鉴定出来的，并且通过与国际财团CARDIoGRAM合作，已经确定了13个新的CAD相关基因。
