可通过体外去除的中毒。

Intoxications amenable to extracorporeal removal.

机构信息

Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA.

出版信息

Adv Chronic Kidney Dis. 2011 May;18(3):167-71. doi: 10.1053/j.ackd.2010.10.007.

DOI:10.1053/j.ackd.2010.10.007

Abstract

Extracorporeal removal of drugs was first attempted in 1913, by John Jacob Abel. Previously known to be a rarity, dialysis and to a lesser extent hemoperfusion have now become obvious tools for nephrologists in treating life-threatening cases of poisoning. Moreover, for dialysis patients, dialysis along with chelation therapy for removal of aluminum, once known to be common in the United States, is resurging in some countries. This article will discuss the principles of drug removal, the indications for dialysis, and give a brief outline of poisons amenable to dialysis.

摘要

1913 年，John Jacob Abel 首次尝试进行药物体外清除。在此之前，透析和血液灌流鲜为人知，现已成为肾病学家治疗危及生命的中毒病例的重要手段。此外，对于接受透析治疗的患者，除了螯合疗法以去除在美国曾很常见的铝之外，透析疗法在一些国家也重新流行起来。本文将讨论药物清除的原理、透析的适应证，并简要概述可通过透析治疗的毒物。