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磷酸尿嘧啶核糖基转移酶阳性间叶性肿瘤伴软骨黏液样纤维瘤样特征:一种不常见的形态学表现。

Phosphaturic mesenchymal tumor with chondromyxoid fibroma-like feature: an unusual morphological appearance.

机构信息

Department of Pathology, Tata Memorial Hospital, E. Borges Marg, Parel, Mumbai, India.

出版信息

Skeletal Radiol. 2011 Nov;40(11):1481-5. doi: 10.1007/s00256-011-1159-6. Epub 2011 May 1.

DOI:10.1007/s00256-011-1159-6
PMID:21533894
Abstract

Phosphaturic mesenchymal tumor (PMT) is a rare and distinctive tumor almost always associated with oncogenic osteomalacia. This tumor is often misdiagnosed due to its widely varied histomorphological spectrum. More recently the term PMT or its variants has been used whatever the histomorphological features. Herein, we present a case of a 32-year-old woman who presented with a 2-year history of oncogenic osteomalacia. The clinical examination failed to detect any tumor. The F-18 FDG PET scan and subsequent MRI revealed a tumor in the soft tissues of the right popliteal fossa. The histological features resembled a chondromyxoid fibroma (CMF), a feature documented only in two cases so far.

摘要

磷酸尿嘧啶基质肿瘤(PMT)是一种罕见且独特的肿瘤,几乎总是与癌性骨软化症相关。由于其广泛的组织形态学谱,这种肿瘤经常被误诊。最近,无论组织形态学特征如何,术语 PMT 或其变体都被使用。在此,我们报告了一名 32 岁女性的病例,她患有癌性骨软化症已有 2 年病史。临床检查未发现任何肿瘤。F-18 FDG PET 扫描和随后的 MRI 显示右腘窝软组织中有一个肿瘤。组织学特征类似于软骨黏液样纤维瘤(CMF),迄今为止仅在两例中记录到这种特征。

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Front Oncol. 2024 Dec 19;14:1501499. doi: 10.3389/fonc.2024.1501499. eCollection 2024.
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CT and MR imaging features in phosphaturic mesenchymal tumor-mixed connective tissue: A case report.伴混合性结缔组织的磷尿性间叶肿瘤的CT和MR成像特征:病例报告
Oncol Lett. 2018 Apr;15(4):4970-4978. doi: 10.3892/ol.2018.7945. Epub 2018 Feb 5.
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Immunohistochemical and molecular detection of the expression of FGF23 in phosphaturic mesenchymal tumors including the non-phosphaturic variant.

本文引用的文献

1
Phosphaturic mesenchymal tumor of ethmoid sinus.筛窦磷酸尿性间叶肿瘤
Indian J Pathol Microbiol. 2010 Apr-Jun;53(2):384-5. doi: 10.4103/0377-4929.64317.
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Mesenchymal phosphaturic neoplasm in the maxillary sinus: a case report.上颌窦间叶性磷酸盐尿性肿瘤:一例报告。
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Phosphaturic mesenchymal tumor: two contrasting cases.磷酸尿性间叶肿瘤:两例对比病例
Skeletal Radiol. 2014 Jun;43(6):841-5. doi: 10.1007/s00256-013-1798-x. Epub 2014 Jan 9.
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Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature.下颌骨混合性结缔组织变异型促排磷间叶肿瘤:1例报告并文献复习
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5
A haemangiopericytoma of the ethmoid sinus causing oncogenic osteomalacia: a case report and review of the literature.筛窦血管外皮细胞瘤致肿瘤性骨软化症:一例报告并文献复习
Int J Oral Maxillofac Surg. 2007 Oct;36(10):956-8. doi: 10.1016/j.ijom.2007.03.005. Epub 2007 May 10.
6
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Clin Nucl Med. 2007 Apr;32(4):300-1. doi: 10.1097/01.rlu.0000257180.03964.51.
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Oncogenic osteomalacia: induced by tumor, cured by surgery.致癌性骨软化症:由肿瘤诱发,手术治愈。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 May;103(5):636-41. doi: 10.1016/j.tripleo.2005.12.027. Epub 2007 Feb 20.
8
Oncogenic osteomalacia caused by phosphaturic mesenchymal tumor of the temporal bone.颞骨磷酸尿性间叶肿瘤所致的致癌性骨软化症。
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Tumor-induced osteomalacia.肿瘤诱导的骨软化症。
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10
Hypophosphaturic mesenchymal tumor of the ethmoid associated with oncogenic osteomalacia.与致癌性骨软化症相关的筛窦低磷性间叶肿瘤
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