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[智利圣地亚哥德国诊所的结直肠癌筛查]

[Colorectal cancer screening at Clínica Alemana, Santiago de Chile].

作者信息

Silva Maria de los Angeles, Santander Ricardo, Gobelet Jaquelina, Valdivieso Eduardo, Ramírez Maria Antonieta, Sáenz Roque, Alarcón Gonzalo, Elías Soledad, Olivares Lizzy

机构信息

The Latin-American WGO and OMED Gastrointestinal Endoscopy Training Center, Clínica Alemana, Chile.

出版信息

Acta Gastroenterol Latinoam. 2011 Mar;41(1):10-6.

Abstract

INTRODUCTION

Colorectal cancer (CRC) incidence is rapidly increasing. It has been demonstrated that it can be prevented and cured when the diagnosis is made in early stages.

OBJECTIVE

For this reason it is necessary to apply a screening program in asymptomatic patients.

METHOD

Since 2003, we conducted a CRC screening plan called "Mes del Colon" at Clínica Alemana Santiago. A press and local diffusion campaign was designed. Open to the community CRC talks were scheduled. An ad hoc database was designed. An informed consent was available. Patients older than 50 years and high risk patients were included. Total colonoscopy and a medical interview after the procedure were included in the plan with favorable economic conditions.

RESULTS

Since 2003, 1158 patients were included The 1.8% of them were excluded because of incomplete data or because they did not meet the inclusion criteria. The 54% of patients were women. Mean age was 58.4 years old and mean body mass index 25.5 kg/m2. Polipoid lesions were seen in 45% of the patients. Six (1%) of them were adenocarcinomas, 291 (57%) adenomas (98% tubular adenomas), 189 (37%) hyperplastic polyps and 25 (5%) miscellaneous lesions. In this series, the necessary number to investigate for 1 adenoma was 3.9.

CONCLUSIONS

CRC prevention campaigns are needed due to the continuous increase of the incidence in our country. The detection of precursor or early lesions that are longstanding before becoming advanced cancer allows its treatment avoiding progression.

摘要

引言

结直肠癌(CRC)的发病率正在迅速上升。已经证明,早期诊断时它是可以预防和治愈的。

目的

因此,有必要对无症状患者实施筛查计划。

方法

自2003年以来,我们在圣地亚哥德国诊所开展了一项名为“结肠月”的结直肠癌筛查计划。设计了一项媒体宣传和本地推广活动。安排了面向社区的结直肠癌讲座。设计了一个专门的数据库。提供了知情同意书。纳入了50岁以上的患者和高危患者。该计划包括在经济条件允许的情况下进行全结肠镜检查以及检查后的医学访谈。

结果

自2003年以来,共纳入1158例患者。其中1.8%的患者因数据不完整或不符合纳入标准而被排除。54%的患者为女性。平均年龄为58.4岁,平均体重指数为25.5kg/m²。45%的患者发现有息肉样病变。其中6例(1%)为腺癌,291例(57%)为腺瘤(98%为管状腺瘤),189例(37%)为增生性息肉,25例(5%)为其他病变。在这个系列中,发现1例腺瘤所需的调查人数为3.9。

结论

由于我国发病率持续上升,需要开展结直肠癌预防活动。检测出在发展为晚期癌症之前长期存在的癌前病变或早期病变,可对其进行治疗以避免病情进展。

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