Backes Carl H, Markham Kara, Moorehead Pamela, Cordero Leandro, Nankervis Craig A, Giannone Peter J
Department of Pediatrics, College of Medicine, The Ohio State University and Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.
J Pregnancy. 2011;2011:214365. doi: 10.1155/2011/214365. Epub 2011 Apr 4.
Preeclampsia is a multiorgan, heterogeneous disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Optimal strategies in the care of the women with preeclampsia have not been fully elucidated, leaving physicians with incomplete data to guide their clinical decision making. Because preeclampsia is a progressive disorder, in some circumstances, delivery is needed to halt the progression to the benefit of the mother and fetus. However, the need for premature delivery has adverse effects on important neonatal outcomes not limited to the most premature infants. Late-preterm infants account for approximately two thirds of all preterm deliveries and are at significant risk for morbidity and mortality. Reviewed is the current literature in the diagnosis and obstetrical management of preeclampsia, the outcomes of late-preterm infants, and potential strategies to optimize fetal outcomes in pregnancies complicated by preeclampsia.
子痫前期是一种多器官、异质性的妊娠疾病，与孕产妇和新生儿的高发病率及死亡率相关。子痫前期患者护理的最佳策略尚未完全阐明，使得医生在临床决策时缺乏完整的数据指导。由于子痫前期是一种进行性疾病，在某些情况下，需要分娩以阻止疾病进展，从而使母亲和胎儿受益。然而，早产的必要性对重要的新生儿结局有不利影响，且不仅限于极早产儿。晚期早产儿约占所有早产分娩的三分之二，并且有很高的发病和死亡风险。本文综述了子痫前期诊断和产科管理的当前文献、晚期早产儿的结局，以及优化子痫前期合并妊娠胎儿结局的潜在策略。
