Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of Healthcare Quality Promotion, Atlanta, GA 30333, USA.
Public Health Rep. 2011 May-Jun;126(3):312-7. doi: 10.1177/003335491112600303.
The 2009 pandemic influenza A (H1N1) outbreak was associated with an increased use of antiviral agents and highlighted the role of population-based monitoring for related adverse drug events (ADEs). An ongoing, nationally representative emergency department-based surveillance system was used to identify and characterize ADEs during the pandemic. Active surveillance for ADEs successfully provided timely, population-based data during the pandemic. Increases in antiviral ADEs paralleled increases in prescribing. Type and severity of ADEs were similar across all seasons.
2009 年的甲型 H1N1 流感大流行与抗病毒药物的使用增加有关，凸显了基于人群的监测在相关药物不良事件（ADE）中的作用。正在进行的全国代表性的基于急诊的监测系统被用于识别和描述大流行期间的 ADE。主动监测 ADE 在大流行期间成功提供了及时的、基于人群的数据。抗病毒 ADE 的增加与处方的增加平行。所有季节的 ADE 的类型和严重程度相似。
