Academic Unit of Radiology, University of Sheffield, Sheffield, UK.
Eur Radiol. 2011 Sep;21(9):1820-30. doi: 10.1007/s00330-011-2144-0. Epub 2011 May 10.
Developmental delay is a common problem in paediatric practice and many children with developmental delay are referred for MR imaging. Our study was performed as part of a continuing audit process to optimise our MR protocol and case selection.
We performed MR imaging and spectroscopy protocol on 157 children with developmental delay. We analysed the effect of these interventions by looking at the overall detection rate of relevant pathology and in particular subgroups of the children.
71% of the children had normal MR imaging, 10% had non-specific findings and 19% had specific abnormalities on MR imaging. The overall risk of having a specific structural abnormality with isolated developmental was 7.5% but if other neurological symptoms/signs were present the risk was 28%. Two children had abnormal spectroscopic findings, one with tuberous sclerosis and the other with absent brain creatine.
Case selection for MR imaging is important in children with developmental delay. The best strategies for selecting children for MR are either; not performing MR with developmental delay in one domain only or performing MR with developmental delay in three or four domains or if there are other neurological features.
发育迟缓是儿科临床中的常见问题，许多发育迟缓的儿童需要进行磁共振成像（MR）检查。我们的研究是作为持续审核过程的一部分进行的，旨在优化我们的 MR 方案和病例选择。
我们对 157 例发育迟缓的儿童进行了 MR 成像和波谱分析检查。我们通过观察相关病理学的整体检出率以及儿童的特定亚组，分析了这些干预措施的效果。
71%的儿童 MR 成像正常，10%的儿童有非特异性表现，19%的儿童有特定的 MR 成像异常。孤立性发育性发育迟缓的特定结构性异常的总体风险为 7.5%，但如果存在其他神经症状/体征，则风险为 28%。有两名儿童的波谱检查结果异常，其中一例为结节性硬化症，另一例为脑creatine 缺失。
发育迟缓儿童的 MR 成像病例选择很重要。对于发育迟缓的儿童，选择进行 MR 检查的最佳策略是：仅在一个领域存在发育迟缓时不进行 MR 检查，或在三个或四个领域存在发育迟缓时进行 MR 检查，或者存在其他神经特征时进行 MR 检查。
