Mostafa Ahmad E, Geist Volker, Abdel-Wahab Mohamed
Heart Center, Segeberger Kliniken GmbH (Academic Teaching Hospital of the University of Kiel), Bad Segeberg, Germany.
J Invasive Cardiol. 2011 May;23(5):E102-5.
Coronary artery disease has been reported in more than 50% of patients with severe aortic stenosis above the age of 70 years. Combined surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG) is associated with a higher operative risk. Concomitant coronary artery disease also increases the procedural risk of transcatheter aortic valve implantation (TAVI), and hence, a combined strategy for treating both entities needs to be carefully considered. Data regarding TAVI and percutaneous coronary intervention (PCI) as a combined percutaneous procedure are scarce. We report the case of an 84-year-old woman who presented with non-ST segment elevation myocardial infarction and impending pulmonary edema who was diagnosed with severe aortic stenosis and two-vessel coronary artery disease. Because of an elevated logistic Euroscore of 25% and her unstable presentation, percutaneous coronary revascularization and TAVI were successfully performed in a combined percutaneous transfemoral procedure. She had a smooth recovery and rehabilitation period with significant improvement in her symptoms and functional capacity. Thirty-day follow-up, including transthoracic echocardiography and cardiac magnetic resonance imaging, showed a well-functioning prosthetic valve and no signs of residual myocardial ischemia. We therefore conclude that combined PCI and TAVI is feasible and can be associated with good clinical outcomes in selected cases. Further data and experience are needed to evaluate this strategy.
据报道,在70岁以上的重度主动脉瓣狭窄患者中,超过50%患有冠状动脉疾病。联合进行外科主动脉瓣置换术(SAVR)和冠状动脉旁路移植术(CABG)手术风险更高。合并冠状动脉疾病也会增加经导管主动脉瓣植入术(TAVI)的手术风险,因此,需要仔细考虑同时治疗这两种疾病的联合策略。关于TAVI和经皮冠状动脉介入治疗(PCI)作为联合经皮手术的数据很少。我们报告了一例84岁女性患者,她因非ST段抬高型心肌梗死和即将发生的肺水肿就诊,被诊断为重度主动脉瓣狭窄和双支冠状动脉疾病。由于逻辑欧洲评分(logistic Euroscore)高达25%且病情不稳定,经皮冠状动脉血运重建和TAVI在一次联合经股手术中成功完成。她恢复顺利,康复期症状和功能能力有显著改善。包括经胸超声心动图和心脏磁共振成像在内的30天随访显示人工瓣膜功能良好,无残余心肌缺血迹象。因此,我们得出结论,联合PCI和TAVI是可行的,在某些特定病例中可能会有良好的临床结果。需要更多数据和经验来评估这一策略。