Barahona M L, Mora-Encinas J P, Gonzalez-Montano V M, Pozo-Zamorano T, Fernandez-Gil M A
Servicio de Radiodiagnóstico, Complejo Hospitalario, Universitario Infanta Cristina, Badajoz, Espana.
Rev Neurol. 2011 Jun 1;52(11):676-80.
Intracranial hypotension syndrome (IHS) is a syndrome with a variable aetiology and clinical presentation that is, in most cases, caused by leakage of cerebrospinal fluid (CSF) through the thecal sac. Orthostatic headache associated to the typical magnetic resonance imaging (MRI) findings, secondary to depletion of CSF, is the key to a correct diagnosis.
To show the imaging findings that, within a suitable clinical context, allow this condition to be identified and diagnosed.
Decreased CSF volume plays an important role in IHS, which leads to an increase in the compensatory volume of blood, essentially dependent on the venous system. MRI is a sensitive technique in the diagnosis of IHS. Yet, separate findings are unspecific. The MRI findings include diffuse and homogeneous dural enhancement, the presence of small bilateral subdural collections, caudal displacement of the encephalic structures (pseudo-Chiari), dilatation of the cortical and medullar veins, and the recent sign of venous distension. This last sign is a highly sensitive finding of IHS, which tends to disappear following the patient's clinical improvement even before the disappearance of the pachy-meningeal enhancement, and could be used as a marker for response to treatment.
IHS is a condition that is difficult to diagnose clinically for which several typical MRI findings have been reported; both neurologists and radiologists must be familiar with these findings.
颅内低压综合征(IHS)是一种病因和临床表现多样的综合征,在大多数情况下,是由脑脊液(CSF)通过硬脊膜囊漏出所致。与典型磁共振成像(MRI)表现相关的直立性头痛,继发于脑脊液减少,是正确诊断的关键。
展示在合适的临床背景下能够识别和诊断该疾病的影像学表现。
脑脊液容量减少在颅内低压综合征中起重要作用,这会导致血液代偿容量增加,主要依赖于静脉系统。MRI是诊断颅内低压综合征的敏感技术。然而,单独的表现并无特异性。MRI表现包括硬脑膜弥漫性均匀强化、双侧小的硬膜下积液、脑结构尾端移位(假性Chiari畸形)、皮质和髓质静脉扩张以及最近发现的静脉扩张征。最后这个征象是颅内低压综合征的高度敏感表现,即使在硬脑膜强化消失之前,随着患者临床症状改善它也往往会消失,并且可作为治疗反应的标志物。
颅内低压综合征是一种临床诊断困难的疾病,已有多种典型的MRI表现被报道;神经科医生和放射科医生都必须熟悉这些表现。